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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Aboo_0200KEGG: mfe:Mefer_0041 3-isopropylmalate dehydratase, small subunit; TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein. (176 aa)    
Predicted Functional Partners:
leuC
Homoaconitate hydratase family protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 0.998
Aboo_0695
Homoaconitate hydratase family protein; KEGG: mka:MK1440 3-isopropylmalate dehydratase large subunit; TIGRFAM: homoaconitate hydratase family protein; PFAM: aconitate hydratase domain protein.
 0.998
leuC-2
Homoaconitate hydratase family protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 0.997
Aboo_0166
KEGG: aba:Acid345_2964 3-isopropylmalate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase.
  
 
 0.956
leuD
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily.
  
  
 
0.909
Aboo_0128
KEGG: pfu:PF0939 3-isopropylmalate dehydratase small subunit; TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein.
  
  
 
0.908
Aboo_0985
Malate dehydrogenase (oxaloacetate-decarboxylating); KEGG: pho:PH1275 malate oxidoreductase; PFAM: malic protein NAD-binding; malic protein domain protein.
  
 
 0.827
Aboo_1230
PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; KEGG: tte:TTE1336 oxaloacetate decarboxylase.
  
 
 0.816
Aboo_0946
TIGRFAM: pyruvate kinase; KEGG: tte:TTE1815 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta.
  
 
 0.813
Aboo_0059
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: sfu:Sfum_0016 2-oxoglutarate ferredoxin oxidoreductase subunit beta.
   
 
  0.808
Your Current Organism:
Aciduliprofundum boonei
NCBI taxonomy Id: 439481
Other names: A. boonei T469, Aciduliprofundum boonei DSM 19572, Aciduliprofundum boonei T469, Aciduliprofundum boonei str. T469, Aciduliprofundum boonei strain T469
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