STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glmSGlucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (587 aa)    
Predicted Functional Partners:
Aboo_0282
KEGG: mac:MA3024 phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; Belongs to the phosphohexose mutase family.
 
 0.948
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
 
  
0.939
purQ
Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]
    
 0.934
Aboo_1423
Glutamate--ammonia ligase; KEGG: mst:Msp_0234 hypothetical protein; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp.
  
 
 0.933
Aboo_1435
KEGG: tac:Ta1498 glutamine synthetase; TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp.
  
 
 0.933
Aboo_0590
KEGG: tsi:TSIB_0813 phosphoglucose isomerase (PGI); PFAM: glucose-6-phosphate isomerase.
    
  0.901
Aboo_0285
PFAM: Nucleotidyl transferase; transferase hexapeptide repeat containing protein; KEGG: rci:RCIX1434 glucose-1-phosphate thymidylyltransferase.
   
 0.867
Aboo_0314
PFAM: peptidase M50; KEGG: tac:Ta1274 sterol-regulatory element-binding proteins intramembrane protease related protein.
     
 0.710
Aboo_0286
PFAM: protein of unknown function DUF81; KEGG: cpi:Cpin_7258 protein of unknown function DUF81.
       0.701
Aboo_0708
PFAM: Nucleotidyl transferase; Cupin 2 conserved barrel domain protein; KEGG: mth:MTH1523 glucose-1-phosphate adenylyltransferase related protein.
     
 0.606
Your Current Organism:
Aciduliprofundum boonei
NCBI taxonomy Id: 439481
Other names: A. boonei T469, Aciduliprofundum boonei DSM 19572, Aciduliprofundum boonei T469, Aciduliprofundum boonei str. T469, Aciduliprofundum boonei strain T469
Server load: low (16%) [HD]