STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgkKEGG: tvo:TVN0530 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (409 aa)    
Predicted Functional Partners:
Aboo_0431
SMART: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: tex:Teth514_1306 glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 0.999
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 
 0.999
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 
 0.999
apgM
Phosphonopyruvate decarboxylase-related protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
    
 0.924
Aboo_0946
TIGRFAM: pyruvate kinase; KEGG: tte:TTE1815 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta.
 
 
 0.819
rps5
Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy.
 
 
 0.694
rpl4
50S ribosomal protein L4P; Forms part of the polypeptide exit tunnel.
  
 
 0.680
rpl1
Ribosomal protein L1; Binds directly to 23S rRNA. Probably involved in E site tRNA release.
 
  
 0.679
rpl11
Ribosomal protein L11-like protein; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family.
 
 
 0.671
Aboo_0481
TIGRFAM: ribulose-phosphate 3-epimerase; KEGG: tpd:Teth39_1311 ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
  
 
 0.657
Your Current Organism:
Aciduliprofundum boonei
NCBI taxonomy Id: 439481
Other names: A. boonei T469, Aciduliprofundum boonei DSM 19572, Aciduliprofundum boonei T469, Aciduliprofundum boonei str. T469, Aciduliprofundum boonei strain T469
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.