STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hptPhosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. (185 aa)    
Predicted Functional Partners:
guaAB
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
 0.982
Aboo_1162
KEGG: tvo:TVN0999 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase-like; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 0.973
Aboo_0850
SMART: AICARFT/IMPCHase bienzyme formylation region; MGS domain protein; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; KEGG: chy:CHY_1078 bifunctional purine biosynthesis protein PurH; PFAM: AICARFT/IMPCHase bienzyme formylation region; MGS domain protein.
  
 0.971
Aboo_0480
PFAM: PfkB domain protein; KEGG: tac:Ta0880 ribokinase related protein.
  
 0.969
guaAA
GMP synthase, small subunit; Catalyzes the synthesis of GMP from XMP.
  
 
 0.966
Aboo_0281
TIGRFAM: adenosine deaminase; KEGG: aci:ACIAD1245 adenosine deaminase; PFAM: adenosine/AMP deaminase.
    
 0.915
Aboo_1468
KEGG: ppr:PBPRA2246 guanine deaminase; TIGRFAM: guanine deaminase; PFAM: amidohydrolase.
    
 0.915
Aboo_1227
Adenylate kinase; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily.
   
 
  0.905
adkA
KEGG: tvo:TVN0349 adenylate kinase; Belongs to the archaeal adenylate kinase family.
     
  0.900
Aboo_0836
PFAM: phosphoribosyltransferase; KEGG: tac:Ta1351 purine phosphoribosyltransferase related protein.
  
 
 0.838
Your Current Organism:
Aciduliprofundum boonei
NCBI taxonomy Id: 439481
Other names: A. boonei T469, Aciduliprofundum boonei DSM 19572, Aciduliprofundum boonei T469, Aciduliprofundum boonei str. T469, Aciduliprofundum boonei strain T469
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.