STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Aboo_1386PFAM: Protein of unknown function DUF357; KEGG: mfe:Mefer_0888 protein of unknown function DUF357. (97 aa)    
Predicted Functional Partners:
Aboo_1385
PFAM: protein of unknown function DUF87; HerA-ATP synthase, barrel domain; KEGG: mbu:Mbur_0970 hypothetical protein.
       0.687
nac
Ubiquitin-associated- domain-containing protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.
  
     0.606
pan
26S proteasome subunit P45 family; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...]
       0.605
Aboo_1382
PFAM: chromosome segregation and condensation protein ScpA; KEGG: tsi:TSIB_0723 segregation and condensation protein A.
  
     0.592
trmY
Protein of unknown function DUF358; Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs; Belongs to the methyltransferase superfamily. TrmY family.
  
     0.498
Aboo_1488
PFAM: nucleic acid binding OB-fold tRNA/helicase-type; KEGG: hwa:HQ2405A replication factor A.
  
     0.498
rpoL
DNA-directed RNA polymerase subunit L; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
     
 0.491
Aboo_1317
PFAM: Type II secretion system F domain; KEGG: mbu:Mbur_1575 flagellar assembly protein J.
  
     0.476
rpl18e
PFAM: ribosomal protein L15; KEGG: mae:Maeo_1097 50S ribosomal protein L18e; Belongs to the eukaryotic ribosomal protein eL18 family.
  
     0.437
Aboo_0002
KEGG: tvo:TVN0221 signal peptidase I.
  
     0.432
Your Current Organism:
Aciduliprofundum boonei
NCBI taxonomy Id: 439481
Other names: A. boonei T469, Aciduliprofundum boonei DSM 19572, Aciduliprofundum boonei T469, Aciduliprofundum boonei str. T469, Aciduliprofundum boonei strain T469
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