STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Aboo_1460PFAM: NUDIX hydrolase; KEGG: tye:THEYE_A0788 MutT/NUDIX family protein. (176 aa)    
Predicted Functional Partners:
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P).
  
 
 0.913
Aboo_0187
PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase; KEGG: afu:AF0458 phosphomannomutase (pmm).
  
 
  0.904
Aboo_1538
KEGG: tvo:TVN0620 phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; Belongs to the phosphohexose mutase family.
  
 
  0.904
Aboo_1461
hydroxymethylglutaryl-CoA reductase, degradative; KEGG: afu:AF1736 3-hydroxy-3-methylglutaryl-coenzyme A reductase (MvaA); TIGRFAM: hydroxymethylglutaryl-CoA reductase, degradative; Belongs to the HMG-CoA reductase family.
     
 0.804
flpA
Fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
  
 0.632
Aboo_0501
DEAD/DEAH box helicase domain protein; KEGG: tga:TGAM_1910 ATP-dependent RNA helicase, DEAD-family (DeaD); PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; Belongs to the DEAD box helicase family.
  
 0.632
Aboo_1462
PFAM: APHP domain protein; Peptidase S53 propeptide; peptidase M6 immune inhibitor A; KEGG: aba:Acid345_2438 peptidase S8 and S53, subtilisin, kexin, sedolisin.
       0.545
Aboo_0314
PFAM: peptidase M50; KEGG: tac:Ta1274 sterol-regulatory element-binding proteins intramembrane protease related protein.
    
 0.509
rrp42
3' exoribonuclease; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.
    
 0.461
Aboo_1463
KEGG: mtp:Mthe_0549 isocitrate dehydrogenase (NAD(+)); PFAM: isocitrate/isopropylmalate dehydrogenase.
       0.426
Your Current Organism:
Aciduliprofundum boonei
NCBI taxonomy Id: 439481
Other names: A. boonei T469, Aciduliprofundum boonei DSM 19572, Aciduliprofundum boonei T469, Aciduliprofundum boonei str. T469, Aciduliprofundum boonei strain T469
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.