Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ompRResponse regulator in two-component regulatory system with EnvZ, OmpR family; [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (225 aa)    
Predicted Functional Partners:
envZ
Osmolarity sensor protein EnvZ; [T] COG0642 Signal transduction histidine kinase.
 
 0.996
yycG
Sensory box histidine kinase YycG; [T] COG0642 Signal transduction histidine kinase.
 
 0.935
chvG
[T] COG0642 Signal transduction histidine kinase.
 
 0.912
EDZ59882.1
Ammonium transporter family protein; [TK] COG2208 Serine phosphatase RsbU, regulator of sigma subunit.
  
 0.910
rsbU
Sigma factor SigB regulation protein; [TK] COG2208 Serine phosphatase RsbU, regulator of sigma subunit.
  
 0.893
ntrY
Nitrogen regulation protein NtrY; [T] COG0642 Signal transduction histidine kinase.
  
 
 0.835
EDZ60156.1
Putative adenylate/guanylate cyclase transmembrane protein; [T] COG4252 Predicted transmembrane sensor domain.
   
 0.824
regB
Sensor histidine kinase (two component sensor); [T] COG0642 Signal transduction histidine kinase.
  
 0.812
fdsB
NAD-dependent formate dehydrogenase beta subunit; [C] COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit.
   
   0.797
petP
[K] COG1846 Transcriptional regulators.
     
 0.780
Your Current Organism:
Pelagibacter sp. HTCC7211
NCBI taxonomy Id: 439493
Other names: C. Pelagibacter sp. HTCC7211, Candidatus Pelagibacter sp. HTCC7211
Server load: low (20%) [HD]