node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EDZ46602.1 | EDZ48199.1 | RBY4I_1818 | RBY4I_3419 | 2-isopropylmalate synthase/homocitrate synthase family protein; [E] COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain family; [I] COG1024 Enoyl-CoA hydratase/carnithine racemase. | 0.582 |
EDZ46602.1 | EDZ48662.1 | RBY4I_1818 | RBY4I_3885 | 2-isopropylmalate synthase/homocitrate synthase family protein; [E] COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family. | KR domain family; [IQ] COG0304 3-oxoacyl-(acyl-carrier-protein) synthase. | 0.915 |
EDZ46602.1 | glcB | RBY4I_1818 | RBY4I_2264 | 2-isopropylmalate synthase/homocitrate synthase family protein; [E] COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.835 |
EDZ46602.1 | gltA | RBY4I_1818 | RBY4I_2771 | 2-isopropylmalate synthase/homocitrate synthase family protein; [E] COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family. | [C] COG0372 Citrate synthase; Belongs to the citrate synthase family. | 0.533 |
EDZ46602.1 | leuA | RBY4I_1818 | RBY4I_1543 | 2-isopropylmalate synthase/homocitrate synthase family protein; [E] COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.867 |
EDZ46602.1 | mmsA | RBY4I_1818 | RBY4I_1136 | 2-isopropylmalate synthase/homocitrate synthase family protein; [E] COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family. | [C] COG1012 NAD-dependent aldehyde dehydrogenases. | 0.831 |
EDZ46881.1 | EDZ48199.1 | RBY4I_2098 | RBY4I_3419 | [G] COG0362 6-phosphogluconate dehydrogenase. | 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain family; [I] COG1024 Enoyl-CoA hydratase/carnithine racemase. | 0.861 |
EDZ46881.1 | RBY4I_627 | RBY4I_2098 | RBY4I_627 | [G] COG0362 6-phosphogluconate dehydrogenase. | Oxidoreductase, zinc-binding dehydrogenase family; [CR] COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases. | 0.851 |
EDZ46881.1 | glcB | RBY4I_2098 | RBY4I_2264 | [G] COG0362 6-phosphogluconate dehydrogenase. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.451 |
EDZ46881.1 | gltA | RBY4I_2098 | RBY4I_2771 | [G] COG0362 6-phosphogluconate dehydrogenase. | [C] COG0372 Citrate synthase; Belongs to the citrate synthase family. | 0.816 |
EDZ46881.1 | mmsA | RBY4I_2098 | RBY4I_1136 | [G] COG0362 6-phosphogluconate dehydrogenase. | [C] COG1012 NAD-dependent aldehyde dehydrogenases. | 0.884 |
EDZ46881.1 | mmsB | RBY4I_2098 | RBY4I_3862 | [G] COG0362 6-phosphogluconate dehydrogenase. | [G] COG0362 6-phosphogluconate dehydrogenase; Belongs to the HIBADH-related family. | 0.712 |
EDZ48199.1 | EDZ46602.1 | RBY4I_3419 | RBY4I_1818 | 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain family; [I] COG1024 Enoyl-CoA hydratase/carnithine racemase. | 2-isopropylmalate synthase/homocitrate synthase family protein; [E] COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.582 |
EDZ48199.1 | EDZ46881.1 | RBY4I_3419 | RBY4I_2098 | 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain family; [I] COG1024 Enoyl-CoA hydratase/carnithine racemase. | [G] COG0362 6-phosphogluconate dehydrogenase. | 0.861 |
EDZ48199.1 | EDZ48662.1 | RBY4I_3419 | RBY4I_3885 | 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain family; [I] COG1024 Enoyl-CoA hydratase/carnithine racemase. | KR domain family; [IQ] COG0304 3-oxoacyl-(acyl-carrier-protein) synthase. | 0.967 |
EDZ48199.1 | RBY4I_627 | RBY4I_3419 | RBY4I_627 | 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain family; [I] COG1024 Enoyl-CoA hydratase/carnithine racemase. | Oxidoreductase, zinc-binding dehydrogenase family; [CR] COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases. | 0.866 |
EDZ48199.1 | accB | RBY4I_3419 | RBY4I_3642 | 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain family; [I] COG1024 Enoyl-CoA hydratase/carnithine racemase. | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.658 |
EDZ48199.1 | glcB | RBY4I_3419 | RBY4I_2264 | 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain family; [I] COG1024 Enoyl-CoA hydratase/carnithine racemase. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.719 |
EDZ48199.1 | gltA | RBY4I_3419 | RBY4I_2771 | 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain family; [I] COG1024 Enoyl-CoA hydratase/carnithine racemase. | [C] COG0372 Citrate synthase; Belongs to the citrate synthase family. | 0.946 |
EDZ48199.1 | leuA | RBY4I_3419 | RBY4I_1543 | 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain family; [I] COG1024 Enoyl-CoA hydratase/carnithine racemase. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.582 |