STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ubiG3-demethylubiquinone-9 3-O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. (248 aa)    
Predicted Functional Partners:
EDZ48394.1
Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; [C] COG0644 Dehydrogenases (flavoproteins).
 
 
 0.982
EDZ48532.1
[HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.
 
 
 0.968
ubiA
4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
 
 0.881
RBY4I_414
Methyltransferase, UbiE/COQ5 family; [QR] COG0500 SAM-dependent methyltransferases.
  
 0.849
ubiB
2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily.
  
 
 0.750
RBY4I_562
Cyclase/dehydrase; [I] COG2867 Oligoketide cyclase/lipid transport protein.
  
   
 0.734
gltA
[C] COG0372 Citrate synthase; Belongs to the citrate synthase family.
 
   
 0.725
ubiE-2
Ubiquinone biosynthesis methyltransferase COQ5; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).
  
 0.695
cysC
ATP-sulfurylase family; Catalyzes the synthesis of activated sulfate.
    
 0.688
pip
Proline iminopeptidase; [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); Belongs to the peptidase S33 family.
       0.686
Your Current Organism:
Rhodobacterales bacterium Y4I
NCBI taxonomy Id: 439496
Other names: R. bacterium Y4I
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