EDZ46118.1 protein (Rhodobacterales bacterium Y4I)

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EDZ46118.1

Homocysteine S-methyltransferase; [E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. (340 aa)

Predicted Functional Partners:

EDZ46085.1

0.998

EDZ46385.1

0.994

EDZ48231.1

0.983

ahcY

0.950

metK

0.948

metF_2

0.946

metY

0.943

metF_1

0.923

hom

0.895

EDZ47359.1

0.860

Your Current Organism:

Rhodobacterales bacterium Y4I

NCBI taxonomy Id: 439496
Other names: R. bacterium Y4I

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EDZ46085.1	EDZ46118.1	RBY4I_1297	RBY4I_1330	Pterin-binding enzyme domain protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain.	Homocysteine S-methyltransferase; [E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain.	0.998
EDZ46085.1	EDZ46385.1	RBY4I_1297	RBY4I_1599	Pterin-binding enzyme domain protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain.	5-methyltetrahydrofolate--homocysteine S-methyltransferase; [I] COG2185 Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding).	0.993
EDZ46085.1	EDZ47359.1	RBY4I_1297	RBY4I_2577	Pterin-binding enzyme domain protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain.	Luciferase-like monooxygenase family; [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins.	0.845
EDZ46085.1	EDZ48231.1	RBY4I_1297	RBY4I_3451	Pterin-binding enzyme domain protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain.	[E] COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.928
EDZ46085.1	ahcY	RBY4I_1297	RBY4I_2736	Pterin-binding enzyme domain protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain.	Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.	0.903
EDZ46085.1	hom	RBY4I_1297	RBY4I_3444	Pterin-binding enzyme domain protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain.	[E] COG0460 Homoserine dehydrogenase.	0.905
EDZ46085.1	metF_1	RBY4I_1297	RBY4I_684	Pterin-binding enzyme domain protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain.	[E] COG0685 5,10-methylenetetrahydrofolate reductase.	0.991
EDZ46085.1	metF_2	RBY4I_1297	RBY4I_2291	Pterin-binding enzyme domain protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain.	[E] COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.958
EDZ46085.1	metK	RBY4I_1297	RBY4I_481	Pterin-binding enzyme domain protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain.	Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	0.897
EDZ46085.1	metY	RBY4I_1297	RBY4I_3117	Pterin-binding enzyme domain protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain.	O-acetylhomoserine sulfhydrylase; [E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.	0.879
EDZ46118.1	EDZ46085.1	RBY4I_1330	RBY4I_1297	Homocysteine S-methyltransferase; [E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain.	Pterin-binding enzyme domain protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain.	0.998
EDZ46118.1	EDZ46385.1	RBY4I_1330	RBY4I_1599	Homocysteine S-methyltransferase; [E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain.	5-methyltetrahydrofolate--homocysteine S-methyltransferase; [I] COG2185 Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding).	0.994
EDZ46118.1	EDZ47359.1	RBY4I_1330	RBY4I_2577	Homocysteine S-methyltransferase; [E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain.	Luciferase-like monooxygenase family; [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins.	0.860
EDZ46118.1	EDZ48231.1	RBY4I_1330	RBY4I_3451	Homocysteine S-methyltransferase; [E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain.	[E] COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.983
EDZ46118.1	ahcY	RBY4I_1330	RBY4I_2736	Homocysteine S-methyltransferase; [E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain.	Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.	0.950
EDZ46118.1	hom	RBY4I_1330	RBY4I_3444	Homocysteine S-methyltransferase; [E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain.	[E] COG0460 Homoserine dehydrogenase.	0.895
EDZ46118.1	metF_1	RBY4I_1330	RBY4I_684	Homocysteine S-methyltransferase; [E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain.	[E] COG0685 5,10-methylenetetrahydrofolate reductase.	0.923
EDZ46118.1	metF_2	RBY4I_1330	RBY4I_2291	Homocysteine S-methyltransferase; [E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain.	[E] COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.946
EDZ46118.1	metK	RBY4I_1330	RBY4I_481	Homocysteine S-methyltransferase; [E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain.	Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	0.948
EDZ46118.1	metY	RBY4I_1330	RBY4I_3117	Homocysteine S-methyltransferase; [E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain.	O-acetylhomoserine sulfhydrylase; [E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.	0.943