| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDZ46728.1 | EDZ47359.1 | RBY4I_1945 | RBY4I_2577 | 5,10-methenyltetrahydrofolate synthetase; [H] COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Luciferase-like monooxygenase family; [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins. | 0.780 |
| EDZ46728.1 | EDZ48649.1 | RBY4I_1945 | RBY4I_3872 | 5,10-methenyltetrahydrofolate synthetase; [H] COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | [S] COG1692 Uncharacterized protein conserved in bacteria. | 0.638 |
| EDZ46728.1 | fhs_1 | RBY4I_1945 | RBY4I_2369 | 5,10-methenyltetrahydrofolate synthetase; [H] COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Formate--tetrahydrofolate ligase; [F] COG2759 Formyltetrahydrofolate synthetase. | 0.572 |
| EDZ46728.1 | fhs_2 | RBY4I_1945 | RBY4I_1241 | 5,10-methenyltetrahydrofolate synthetase; [H] COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Formate--tetrahydrofolate ligase; [F] COG2759 Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family. | 0.572 |
| EDZ46728.1 | folD | RBY4I_1945 | RBY4I_2826 | 5,10-methenyltetrahydrofolate synthetase; [H] COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Bifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.803 |
| EDZ46728.1 | folD-2 | RBY4I_1945 | RBY4I_2964 | 5,10-methenyltetrahydrofolate synthetase; [H] COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Bifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.803 |
| EDZ46728.1 | mgtE | RBY4I_1945 | RBY4I_2260 | 5,10-methenyltetrahydrofolate synthetase; [H] COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Magnesium transporter; Acts as a magnesium transporter. | 0.831 |
| EDZ46728.1 | pheT | RBY4I_1945 | RBY4I_3995 | 5,10-methenyltetrahydrofolate synthetase; [H] COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | [J] COG0072 Phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.667 |
| EDZ46728.1 | purH | RBY4I_1945 | RBY4I_1730 | 5,10-methenyltetrahydrofolate synthetase; [H] COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Bifunctional purine biosynthesis protein PurH; [F] COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful). | 0.580 |
| EDZ46728.1 | purN | RBY4I_1945 | RBY4I_3597 | 5,10-methenyltetrahydrofolate synthetase; [H] COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.812 |
| EDZ47359.1 | EDZ46728.1 | RBY4I_2577 | RBY4I_1945 | Luciferase-like monooxygenase family; [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins. | 5,10-methenyltetrahydrofolate synthetase; [H] COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 0.780 |
| EDZ47359.1 | fhs_1 | RBY4I_2577 | RBY4I_2369 | Luciferase-like monooxygenase family; [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins. | Formate--tetrahydrofolate ligase; [F] COG2759 Formyltetrahydrofolate synthetase. | 0.839 |
| EDZ47359.1 | fhs_2 | RBY4I_2577 | RBY4I_1241 | Luciferase-like monooxygenase family; [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins. | Formate--tetrahydrofolate ligase; [F] COG2759 Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family. | 0.839 |
| EDZ47359.1 | folD | RBY4I_2577 | RBY4I_2826 | Luciferase-like monooxygenase family; [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins. | Bifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.902 |
| EDZ47359.1 | folD-2 | RBY4I_2577 | RBY4I_2964 | Luciferase-like monooxygenase family; [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins. | Bifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.902 |
| EDZ47359.1 | pheT | RBY4I_2577 | RBY4I_3995 | Luciferase-like monooxygenase family; [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins. | [J] COG0072 Phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.889 |
| EDZ47359.1 | purH | RBY4I_2577 | RBY4I_1730 | Luciferase-like monooxygenase family; [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins. | Bifunctional purine biosynthesis protein PurH; [F] COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful). | 0.796 |
| EDZ47359.1 | purN | RBY4I_2577 | RBY4I_3597 | Luciferase-like monooxygenase family; [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.865 |
| EDZ48649.1 | EDZ46728.1 | RBY4I_3872 | RBY4I_1945 | [S] COG1692 Uncharacterized protein conserved in bacteria. | 5,10-methenyltetrahydrofolate synthetase; [H] COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 0.638 |
| EDZ48649.1 | mgtE | RBY4I_3872 | RBY4I_2260 | [S] COG1692 Uncharacterized protein conserved in bacteria. | Magnesium transporter; Acts as a magnesium transporter. | 0.604 |