| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDZ48662.1 | pabB | RBY4I_3885 | RBY4I_1963 | KR domain family; [IQ] COG0304 3-oxoacyl-(acyl-carrier-protein) synthase. | Para-aminobenzoate synthase, component I; [HQ] COG1169 Isochorismate synthase. | 0.755 |
| EDZ48662.1 | trpA | RBY4I_3885 | RBY4I_1754 | KR domain family; [IQ] COG0304 3-oxoacyl-(acyl-carrier-protein) synthase. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.417 |
| EDZ48662.1 | trpB | RBY4I_3885 | RBY4I_3038 | KR domain family; [IQ] COG0304 3-oxoacyl-(acyl-carrier-protein) synthase. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.417 |
| EDZ48662.1 | trpC | RBY4I_3885 | RBY4I_3052 | KR domain family; [IQ] COG0304 3-oxoacyl-(acyl-carrier-protein) synthase. | [E] COG0134 Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.423 |
| EDZ48662.1 | trpD | RBY4I_3885 | RBY4I_1265 | KR domain family; [IQ] COG0304 3-oxoacyl-(acyl-carrier-protein) synthase. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.523 |
| EDZ48662.1 | trpG | RBY4I_3885 | RBY4I_3477 | KR domain family; [IQ] COG0304 3-oxoacyl-(acyl-carrier-protein) synthase. | Anthranilate synthase component II; [F] COG0518 GMP synthase - Glutamine amidotransferase domain. | 0.584 |
| aroC | aroE | RBY4I_983 | RBY4I_2743 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.970 |
| aroC | pabB | RBY4I_983 | RBY4I_1963 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Para-aminobenzoate synthase, component I; [HQ] COG1169 Isochorismate synthase. | 0.840 |
| aroC | trpA | RBY4I_983 | RBY4I_1754 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.826 |
| aroC | trpB | RBY4I_983 | RBY4I_3038 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.615 |
| aroC | trpC | RBY4I_983 | RBY4I_3052 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | [E] COG0134 Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.758 |
| aroC | trpD | RBY4I_983 | RBY4I_1265 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.840 |
| aroC | trpF | RBY4I_983 | RBY4I_1579 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | [E] COG0135 Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.619 |
| aroC | trpG | RBY4I_983 | RBY4I_3477 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Anthranilate synthase component II; [F] COG0518 GMP synthase - Glutamine amidotransferase domain. | 0.919 |
| aroE | aroC | RBY4I_2743 | RBY4I_983 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.970 |
| aroE | folP | RBY4I_2743 | RBY4I_1376 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.461 |
| aroE | pabB | RBY4I_2743 | RBY4I_1963 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Para-aminobenzoate synthase, component I; [HQ] COG1169 Isochorismate synthase. | 0.741 |
| aroE | trpA | RBY4I_2743 | RBY4I_1754 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.675 |
| aroE | trpB | RBY4I_2743 | RBY4I_3038 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.668 |
| aroE | trpC | RBY4I_2743 | RBY4I_3052 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | [E] COG0134 Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.872 |