| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDZ46455.1 | pntA_1 | RBY4I_1669 | RBY4I_2004 | Conserved hypothetical protein; [S] COG4949 Uncharacterized membrane-anchored protein conserved in bacteria. | NAD(P)(+) transhydrogenase (AB-specific), alpha subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. | 0.475 |
| EDZ46455.1 | pntB_1 | RBY4I_1669 | RBY4I_758 | Conserved hypothetical protein; [S] COG4949 Uncharacterized membrane-anchored protein conserved in bacteria. | NAD(P)+ transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.500 |
| EDZ47453.1 | RBY4I_385 | RBY4I_2671 | RBY4I_385 | Phosphate acetyl/butyryl transferase subfamily, putative; [C] COG0281 Malic enzyme. | Phosphate acetyl/butyryl transferase subfamily, putative; [C] COG0281 Malic enzyme. | 0.862 |
| EDZ47453.1 | cobB-2 | RBY4I_2671 | RBY4I_1517 | Phosphate acetyl/butyryl transferase subfamily, putative; [C] COG0281 Malic enzyme. | [K] COG0846 NAD-dependent protein deacetylases, SIR2 family; Belongs to the sirtuin family. Class III subfamily. | 0.491 |
| EDZ47453.1 | nadE | RBY4I_2671 | RBY4I_3510 | Phosphate acetyl/butyryl transferase subfamily, putative; [C] COG0281 Malic enzyme. | Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.870 |
| EDZ47453.1 | pheT | RBY4I_2671 | RBY4I_3995 | Phosphate acetyl/butyryl transferase subfamily, putative; [C] COG0281 Malic enzyme. | [J] COG0072 Phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.469 |
| EDZ47453.1 | pntA_1 | RBY4I_2671 | RBY4I_2004 | Phosphate acetyl/butyryl transferase subfamily, putative; [C] COG0281 Malic enzyme. | NAD(P)(+) transhydrogenase (AB-specific), alpha subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. | 0.512 |
| EDZ47453.1 | ppnk | RBY4I_2671 | RBY4I_711 | Phosphate acetyl/butyryl transferase subfamily, putative; [C] COG0281 Malic enzyme. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.759 |
| RBY4I_385 | EDZ47453.1 | RBY4I_385 | RBY4I_2671 | Phosphate acetyl/butyryl transferase subfamily, putative; [C] COG0281 Malic enzyme. | Phosphate acetyl/butyryl transferase subfamily, putative; [C] COG0281 Malic enzyme. | 0.862 |
| RBY4I_385 | cobB-2 | RBY4I_385 | RBY4I_1517 | Phosphate acetyl/butyryl transferase subfamily, putative; [C] COG0281 Malic enzyme. | [K] COG0846 NAD-dependent protein deacetylases, SIR2 family; Belongs to the sirtuin family. Class III subfamily. | 0.491 |
| RBY4I_385 | nadE | RBY4I_385 | RBY4I_3510 | Phosphate acetyl/butyryl transferase subfamily, putative; [C] COG0281 Malic enzyme. | Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.870 |
| RBY4I_385 | pheT | RBY4I_385 | RBY4I_3995 | Phosphate acetyl/butyryl transferase subfamily, putative; [C] COG0281 Malic enzyme. | [J] COG0072 Phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.469 |
| RBY4I_385 | pntA_1 | RBY4I_385 | RBY4I_2004 | Phosphate acetyl/butyryl transferase subfamily, putative; [C] COG0281 Malic enzyme. | NAD(P)(+) transhydrogenase (AB-specific), alpha subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. | 0.512 |
| RBY4I_385 | ppnk | RBY4I_385 | RBY4I_711 | Phosphate acetyl/butyryl transferase subfamily, putative; [C] COG0281 Malic enzyme. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.756 |
| RBY4I_953 | pntA_1 | RBY4I_953 | RBY4I_2004 | [O] COG2020 Putative protein-S-isoprenylcysteine methyltransferase. | NAD(P)(+) transhydrogenase (AB-specific), alpha subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. | 0.576 |
| RBY4I_953 | pntB_1 | RBY4I_953 | RBY4I_758 | [O] COG2020 Putative protein-S-isoprenylcysteine methyltransferase. | NAD(P)+ transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.557 |
| cobB-2 | EDZ47453.1 | RBY4I_1517 | RBY4I_2671 | [K] COG0846 NAD-dependent protein deacetylases, SIR2 family; Belongs to the sirtuin family. Class III subfamily. | Phosphate acetyl/butyryl transferase subfamily, putative; [C] COG0281 Malic enzyme. | 0.491 |
| cobB-2 | RBY4I_385 | RBY4I_1517 | RBY4I_385 | [K] COG0846 NAD-dependent protein deacetylases, SIR2 family; Belongs to the sirtuin family. Class III subfamily. | Phosphate acetyl/butyryl transferase subfamily, putative; [C] COG0281 Malic enzyme. | 0.491 |
| cobB-2 | nadE | RBY4I_1517 | RBY4I_3510 | [K] COG0846 NAD-dependent protein deacetylases, SIR2 family; Belongs to the sirtuin family. Class III subfamily. | Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.928 |
| cobB-2 | pntA_1 | RBY4I_1517 | RBY4I_2004 | [K] COG0846 NAD-dependent protein deacetylases, SIR2 family; Belongs to the sirtuin family. Class III subfamily. | NAD(P)(+) transhydrogenase (AB-specific), alpha subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. | 0.671 |