STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDZ47066.1Transcriptional regulator, MerR family; [K] COG0789 Predicted transcriptional regulators. (133 aa)    
Predicted Functional Partners:
rpoD
Sigma-70 region 3 family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.889
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.646
EDZ46806.1
[GEPR] COG0477 Permeases of the major facilitator superfamily.
 
     0.644
EDZ48440.1
Sensor histidine kinase/response regulator; [T] COG0642 Signal transduction histidine kinase.
   
 
 0.618
RBY4I_125
DnaJ N-terminal domain:DnaJ C terminal domain; [O] COG2214 DnaJ-class molecular chaperone.
  
 
 0.614
EDZ47345.1
DnaJ domain protein; [O] COG2214 DnaJ-class molecular chaperone.
  
 
 0.614
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.614
EDZ46648.1
[T] COG0642 Signal transduction histidine kinase.
   
 0.613
EDZ45902.1
[I] COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit.
     
 0.609
EDZ46123.1
[I] COG2185 Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding).
     
 0.609
Your Current Organism:
Rhodobacterales bacterium Y4I
NCBI taxonomy Id: 439496
Other names: R. bacterium Y4I
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