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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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thiS[H] COG2104 Sulfur transfer protein involved in thiamine biosynthesis. (65 aa)    
Predicted Functional Partners:
thiG
Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
 0.999
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
 
 
 0.995
EDZ48430.1
Hypothetical protein; [H] COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2; uba/thif-type NAD/fad binding fold.
 
 0.995
RBY4I_560
[H] COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase.
 
 
 0.990
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
  
  
 0.982
thiO
[E] COG0665 Glycine/D-amino acid oxidases (deaminating).
 
 
  0.971
RBY4I_911
Hypothetical protein; [H] COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2; uba/thif-type NAD/fad binding fold.
  
 0.957
RBY4I_236
[H] COG0352 Thiamine monophosphate synthase.
  
 
 0.909
EDZ45001.1
FO synthase; [H] COG0502 Biotin synthase and related enzymes.
  
 
  0.863
EDZ45014.1
Conserved hypothetical protein TIGR00423; [HR] COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes.
  
 
  0.863
Your Current Organism:
Rhodobacterales bacterium Y4I
NCBI taxonomy Id: 439496
Other names: R. bacterium Y4I
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