node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EDZ47922.1 | dnaB | RBY4I_3142 | RBY4I_2618 | [L] COG2176 DNA polymerase III, alpha subunit (gram-positive type). | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.736 |
EDZ47922.1 | dnaG | RBY4I_3142 | RBY4I_2477 | [L] COG2176 DNA polymerase III, alpha subunit (gram-positive type). | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.776 |
EDZ47922.1 | polA | RBY4I_3142 | RBY4I_2830 | [L] COG2176 DNA polymerase III, alpha subunit (gram-positive type). | DNA polymerase I superfamily; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.666 |
EDZ47922.1 | rpoC | RBY4I_3142 | RBY4I_3474 | [L] COG2176 DNA polymerase III, alpha subunit (gram-positive type). | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.856 |
EDZ47922.1 | rpoD | RBY4I_3142 | RBY4I_1073 | [L] COG2176 DNA polymerase III, alpha subunit (gram-positive type). | Sigma-70 region 3 family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.601 |
EDZ47922.1 | smpB | RBY4I_3142 | RBY4I_2488 | [L] COG2176 DNA polymerase III, alpha subunit (gram-positive type). | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.544 |
EDZ48044.1 | RBY4I_247 | RBY4I_3264 | RBY4I_247 | Conserved hypothetical protein. | [E] COG4583 Sarcosine oxidase gamma subunit. | 0.648 |
EDZ48044.1 | dnaG | RBY4I_3264 | RBY4I_2477 | Conserved hypothetical protein. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.776 |
EDZ48044.1 | rpoD | RBY4I_3264 | RBY4I_1073 | Conserved hypothetical protein. | Sigma-70 region 3 family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.489 |
RBY4I_247 | EDZ48044.1 | RBY4I_247 | RBY4I_3264 | [E] COG4583 Sarcosine oxidase gamma subunit. | Conserved hypothetical protein. | 0.648 |
RBY4I_247 | dnaG | RBY4I_247 | RBY4I_2477 | [E] COG4583 Sarcosine oxidase gamma subunit. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.721 |
RBY4I_247 | rpoD | RBY4I_247 | RBY4I_1073 | [E] COG4583 Sarcosine oxidase gamma subunit. | Sigma-70 region 3 family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.459 |
dnaB | EDZ47922.1 | RBY4I_2618 | RBY4I_3142 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | [L] COG2176 DNA polymerase III, alpha subunit (gram-positive type). | 0.736 |
dnaB | dnaG | RBY4I_2618 | RBY4I_2477 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.994 |
dnaB | polA | RBY4I_2618 | RBY4I_2830 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA polymerase I superfamily; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.744 |
dnaB | rpoC | RBY4I_2618 | RBY4I_3474 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.724 |
dnaB | rpoD | RBY4I_2618 | RBY4I_1073 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Sigma-70 region 3 family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.556 |
dnaB | smpB | RBY4I_2618 | RBY4I_2488 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.715 |
dnaG | EDZ47922.1 | RBY4I_2477 | RBY4I_3142 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | [L] COG2176 DNA polymerase III, alpha subunit (gram-positive type). | 0.776 |
dnaG | EDZ48044.1 | RBY4I_2477 | RBY4I_3264 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Conserved hypothetical protein. | 0.776 |