STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (362 aa)    
Predicted Functional Partners:
EDZ47453.1
Phosphate acetyl/butyryl transferase subfamily, putative; [C] COG0281 Malic enzyme.
  
 
 0.954
RBY4I_385
Phosphate acetyl/butyryl transferase subfamily, putative; [C] COG0281 Malic enzyme.
  
 
 0.954
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
   
 
 0.929
EDZ47734.1
Thiamine pyrophosphate enzyme, central domain family; [EH] COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.
    
 0.863
RBY4I_777
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 
 0.852
EDZ46376.1
Dehydrogenase E1 component family; [C] COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit.
  
 
 0.816
RBY4I_415
CoA-binding; [C] COG0045 Succinyl-CoA synthetase, beta subunit.
    
 0.795
RBY4I_347
[C] COG1254 Acylphosphatases.
     
 0.782
EDZ45791.1
Coenzyme A transferase; [I] COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit.
     
 0.777
paaN
Phenylacetic acid degradation protein paaN; [C] COG1012 NAD-dependent aldehyde dehydrogenases.
  
 
 0.775
Your Current Organism:
Rhodobacterales bacterium Y4I
NCBI taxonomy Id: 439496
Other names: R. bacterium Y4I
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