STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
RBY4I_263Peptidase M22, glycoprotease; [O] COG0533 Metal-dependent proteases with possible chaperone activity. (198 aa)    
Predicted Functional Partners:
EDZ46278.1
Uncharacterised P-loop hydrolase UPF0079; [R] COG0802 Predicted ATPase or kinase.
 
 0.996
tsaD
Peptidase M22, glycoprotease; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
 
 0.988
RBY4I_874
[R] COG0456 Acetyltransferases.
 
 
 0.882
EDZ46628.1
NifU domain protein; [O] COG0694 Thioredoxin-like proteins and domains.
       0.781
RBY4I_530
[H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase.
  
    0.620
EDZ47701.1
[R] COG1744 Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein.
       0.585
RBY4I_892
[T] COG0589 Universal stress protein UspA and related nucleotide-binding proteins.
       0.577
RBY4I_709
Sua5/YciO/YrdC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.
 
   
 0.560
EDZ48363.1
2-hydroxychromene-2-carboxylate isomerase family protein; [Q] COG2761 Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis.
       0.525
ruvA
Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
  
  
 0.518
Your Current Organism:
Rhodobacterales bacterium Y4I
NCBI taxonomy Id: 439496
Other names: R. bacterium Y4I
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