| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDZ46085.1 | EDZ46118.1 | RBY4I_1297 | RBY4I_1330 | Pterin-binding enzyme domain protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain. | Homocysteine S-methyltransferase; [E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | 0.997 |
| EDZ46085.1 | EDZ46414.1 | RBY4I_1297 | RBY4I_1628 | Pterin-binding enzyme domain protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain. | Cysteine synthase; [E] COG1171 Threonine dehydratase. | 0.598 |
| EDZ46085.1 | EDZ47009.1 | RBY4I_1297 | RBY4I_2227 | Pterin-binding enzyme domain protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain. | Selenium-binding protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | 0.747 |
| EDZ46085.1 | EDZ47558.1 | RBY4I_1297 | RBY4I_2776 | Pterin-binding enzyme domain protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain. | Aminotransferase, classes I and II; [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase. | 0.772 |
| EDZ46085.1 | EDZ47656.1 | RBY4I_1297 | RBY4I_2874 | Pterin-binding enzyme domain protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain. | Conserved hypothetical protein; [O] COG2020 Putative protein-S-isoprenylcysteine methyltransferase. | 0.742 |
| EDZ46085.1 | RBY4I_210 | RBY4I_1297 | RBY4I_210 | Pterin-binding enzyme domain protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain. | 60Kd inner membrane protein; [U] COG0706 Preprotein translocase subunit YidC. | 0.800 |
| EDZ46085.1 | ahcY | RBY4I_1297 | RBY4I_2736 | Pterin-binding enzyme domain protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.852 |
| EDZ46085.1 | hom | RBY4I_1297 | RBY4I_3444 | Pterin-binding enzyme domain protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain. | [E] COG0460 Homoserine dehydrogenase. | 0.853 |
| EDZ46085.1 | metK | RBY4I_1297 | RBY4I_481 | Pterin-binding enzyme domain protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.848 |
| EDZ46085.1 | metY | RBY4I_1297 | RBY4I_3117 | Pterin-binding enzyme domain protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain. | O-acetylhomoserine sulfhydrylase; [E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. | 0.834 |
| EDZ46118.1 | EDZ46085.1 | RBY4I_1330 | RBY4I_1297 | Homocysteine S-methyltransferase; [E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | Pterin-binding enzyme domain protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain. | 0.997 |
| EDZ46118.1 | EDZ46414.1 | RBY4I_1330 | RBY4I_1628 | Homocysteine S-methyltransferase; [E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | Cysteine synthase; [E] COG1171 Threonine dehydratase. | 0.598 |
| EDZ46118.1 | EDZ47009.1 | RBY4I_1330 | RBY4I_2227 | Homocysteine S-methyltransferase; [E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | Selenium-binding protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | 0.746 |
| EDZ46118.1 | EDZ47558.1 | RBY4I_1330 | RBY4I_2776 | Homocysteine S-methyltransferase; [E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | Aminotransferase, classes I and II; [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase. | 0.772 |
| EDZ46118.1 | EDZ47656.1 | RBY4I_1330 | RBY4I_2874 | Homocysteine S-methyltransferase; [E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | Conserved hypothetical protein; [O] COG2020 Putative protein-S-isoprenylcysteine methyltransferase. | 0.742 |
| EDZ46118.1 | RBY4I_210 | RBY4I_1330 | RBY4I_210 | Homocysteine S-methyltransferase; [E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | 60Kd inner membrane protein; [U] COG0706 Preprotein translocase subunit YidC. | 0.809 |
| EDZ46118.1 | ahcY | RBY4I_1330 | RBY4I_2736 | Homocysteine S-methyltransferase; [E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.925 |
| EDZ46118.1 | hom | RBY4I_1330 | RBY4I_3444 | Homocysteine S-methyltransferase; [E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | [E] COG0460 Homoserine dehydrogenase. | 0.823 |
| EDZ46118.1 | metK | RBY4I_1330 | RBY4I_481 | Homocysteine S-methyltransferase; [E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.921 |
| EDZ46118.1 | metY | RBY4I_1330 | RBY4I_3117 | Homocysteine S-methyltransferase; [E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | O-acetylhomoserine sulfhydrylase; [E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. | 0.917 |