STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (462 aa)    
Predicted Functional Partners:
EDZ46118.1
Homocysteine S-methyltransferase; [E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain.
  
 
 0.925
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
 
 
 0.913
EDZ46085.1
Pterin-binding enzyme domain protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain.
    
 0.852
RBY4I_210
60Kd inner membrane protein; [U] COG0706 Preprotein translocase subunit YidC.
  
 
 0.827
metY
O-acetylhomoserine sulfhydrylase; [E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.
     
 0.782
hom
[E] COG0460 Homoserine dehydrogenase.
   
 
  0.768
EDZ47009.1
Selenium-binding protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
     
  0.742
EDZ47558.1
Aminotransferase, classes I and II; [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase.
     
  0.742
EDZ47656.1
Conserved hypothetical protein; [O] COG2020 Putative protein-S-isoprenylcysteine methyltransferase.
     
  0.742
EDZ46414.1
Cysteine synthase; [E] COG1171 Threonine dehydratase.
  
 0.655
Your Current Organism:
Rhodobacterales bacterium Y4I
NCBI taxonomy Id: 439496
Other names: R. bacterium Y4I
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