Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EDZ47655.1Homocysteine S-methyltransferase family protein; [E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. (298 aa)    
Predicted Functional Partners:
EDZ48216.1
[T] COG1956 GAF domain-containing protein.
    
  0.703
RBY4I_791
Transcriptional regulator, AraC family; [K] COG2207 AraC-type DNA-binding domain-containing proteins.
       0.671
EDZ46118.1
Homocysteine S-methyltransferase; [E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain.
  
 
0.658
EDZ46085.1
Pterin-binding enzyme domain protein; [E] COG1410 Methionine synthase I, cobalamin-binding domain.
  
  
 0.655
tyrB
[E] COG1448 Aspartate/tyrosine/aromatic aminotransferase.
  
  
 0.590
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
     
 0.585
RBY4I_286
DNA-binding protein; [K] COG1396 Predicted transcriptional regulators.
  
    0.566
EDZ45822.1
Glycine cleavage T-protein (aminomethyl transferase); [C] COG0578 Glycerol-3-phosphate dehydrogenase; Belongs to the GcvT family.
 
    0.561
hom
[E] COG0460 Homoserine dehydrogenase.
   
 
 0.554
metY
O-acetylhomoserine sulfhydrylase; [E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.
     
 0.542
Your Current Organism:
Rhodobacterales bacterium Y4I
NCBI taxonomy Id: 439496
Other names: R. bacterium Y4I
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