STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RBY4I_292Sodium/solute symporter family protein; [ER] COG0591 Na+/proline symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (594 aa)    
Predicted Functional Partners:
EDZ45948.1
nucleotidyltransferase/CBS/cyclic nucleotide-binding domain protein; [R] COG0517 FOG: CBS domain.
 
  
 0.984
EDZ46537.1
[S] COG4327 Predicted membrane protein.
 
    0.967
EDZ46748.1
Conserved hypothetical protein.
 
    0.890
RBY4I_411
[L] COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases.
 
     0.869
acsA_2
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 0.724
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
 
     0.552
RBY4I_518
AMP-binding enzyme domain protein; [IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
  
  
 0.517
acsA_1
[IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
  
  
 0.517
badA
Benzoate-coenzyme A ligase; [I] COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases.
  
  
 0.513
EDZ47453.1
Phosphate acetyl/butyryl transferase subfamily, putative; [C] COG0281 Malic enzyme.
   
  
 0.442
Your Current Organism:
Rhodobacterales bacterium Y4I
NCBI taxonomy Id: 439496
Other names: R. bacterium Y4I
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