STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fahAFumarylacetoacetase; [Q] COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). (418 aa)    
Predicted Functional Partners:
hmgA
[Q] COG3508 Homogentisate 1,2-dioxygenase.
  
 0.992
maiA
Maleylacetoacetate isomerase; [O] COG0625 Glutathione S-transferase.
 
 0.991
hppD
[ER] COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins.
 
  
 0.866
EDZ48088.1
Metallo-beta-lactamase family protein; [R] COG0491 Zn-dependent hydrolases, including glyoxylases.
 
     0.778
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
  0.773
sdhA
Succinate dehydrogenase, flavoprotein subunit; [H] COG0029 Aspartate oxidase; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
 
  0.761
sdhB
[C] COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 
  0.751
sdhD
[C] COG2142 Succinate dehydrogenase, hydrophobic anchor subunit.
   
 
  0.747
sdhC
[C] COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.
   
 
  0.745
EDZ48085.1
Fumarylacetoacetate hydrolase domain-containing protein 1; [Q] COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).
     
  0.742
Your Current Organism:
Rhodobacterales bacterium Y4I
NCBI taxonomy Id: 439496
Other names: R. bacterium Y4I
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.