| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDZ46380.1 | RBY4I_310 | RBY4I_1594 | RBY4I_310 | [L] COG1466 DNA polymerase III, delta subunit. | Transcriptional regulator, MerR family; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | 0.673 |
| EDZ46380.1 | dnaN | RBY4I_1594 | RBY4I_2348 | [L] COG1466 DNA polymerase III, delta subunit. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.992 |
| EDZ46380.1 | dnaX | RBY4I_1594 | RBY4I_905 | [L] COG1466 DNA polymerase III, delta subunit. | DNA polymerase III, tau subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.993 |
| EDZ46380.1 | holB | RBY4I_1594 | RBY4I_1217 | [L] COG1466 DNA polymerase III, delta subunit. | [L] COG2812 DNA polymerase III, gamma/tau subunits. | 0.996 |
| EDZ48643.1 | RBY4I_310 | RBY4I_3866 | RBY4I_310 | Hypothetical protein; [C] COG2218 Formylmethanofuran dehydrogenase subunit C; Conserved region in glutamate synthase family. | Transcriptional regulator, MerR family; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | 0.851 |
| EDZ48643.1 | dnaN | RBY4I_3866 | RBY4I_2348 | Hypothetical protein; [C] COG2218 Formylmethanofuran dehydrogenase subunit C; Conserved region in glutamate synthase family. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.453 |
| EDZ48643.1 | rpoB | RBY4I_3866 | RBY4I_1412 | Hypothetical protein; [C] COG2218 Formylmethanofuran dehydrogenase subunit C; Conserved region in glutamate synthase family. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.427 |
| RBY4I_310 | EDZ46380.1 | RBY4I_310 | RBY4I_1594 | Transcriptional regulator, MerR family; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | [L] COG1466 DNA polymerase III, delta subunit. | 0.673 |
| RBY4I_310 | EDZ48643.1 | RBY4I_310 | RBY4I_3866 | Transcriptional regulator, MerR family; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | Hypothetical protein; [C] COG2218 Formylmethanofuran dehydrogenase subunit C; Conserved region in glutamate synthase family. | 0.851 |
| RBY4I_310 | cobl | RBY4I_310 | RBY4I_3532 | Transcriptional regulator, MerR family; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | precorrin-6Y C(5,15)-methyltransferase (decarboxylating); [H] COG2242 Precorrin-6B methylase 2. | 0.664 |
| RBY4I_310 | dnaN | RBY4I_310 | RBY4I_2348 | Transcriptional regulator, MerR family; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.673 |
| RBY4I_310 | dnaX | RBY4I_310 | RBY4I_905 | Transcriptional regulator, MerR family; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | DNA polymerase III, tau subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.760 |
| RBY4I_310 | fabH | RBY4I_310 | RBY4I_2250 | Transcriptional regulator, MerR family; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | 3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. | 0.721 |
| RBY4I_310 | holB | RBY4I_310 | RBY4I_1217 | Transcriptional regulator, MerR family; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | [L] COG2812 DNA polymerase III, gamma/tau subunits. | 0.617 |
| RBY4I_310 | ihfA | RBY4I_310 | RBY4I_1620 | Transcriptional regulator, MerR family; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | Integration host factor, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | 0.972 |
| RBY4I_310 | rpoB | RBY4I_310 | RBY4I_1412 | Transcriptional regulator, MerR family; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.661 |
| RBY4I_310 | rpsG | RBY4I_310 | RBY4I_314 | Transcriptional regulator, MerR family; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.848 |
| cobl | RBY4I_310 | RBY4I_3532 | RBY4I_310 | precorrin-6Y C(5,15)-methyltransferase (decarboxylating); [H] COG2242 Precorrin-6B methylase 2. | Transcriptional regulator, MerR family; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | 0.664 |
| dnaN | EDZ46380.1 | RBY4I_2348 | RBY4I_1594 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | [L] COG1466 DNA polymerase III, delta subunit. | 0.992 |
| dnaN | EDZ48643.1 | RBY4I_2348 | RBY4I_3866 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Hypothetical protein; [C] COG2218 Formylmethanofuran dehydrogenase subunit C; Conserved region in glutamate synthase family. | 0.453 |