STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
trxBThioredoxin-disulfide reductase; [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (313 aa)    
Predicted Functional Partners:
trx
Thioredoxin; [OC] COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family.
 
 0.994
EDZ47425.1
Peroxidase; [O] COG1225 Peroxiredoxin.
  
 
 0.907
RBY4I_374
Thioredoxin; [OC] COG0526 Thiol-disulfide isomerase and thioredoxins.
  
 0.907
EDZ46636.1
Hypothetical protein; [OC] COG0526 Thiol-disulfide isomerase and thioredoxins; thioredoxin domain.
  
 0.898
EDZ47373.1
Periplasmic protein thiol; [OC] COG0526 Thiol-disulfide isomerase and thioredoxins.
  
 0.873
EDZ48295.1
Redoxin; [OC] COG0526 Thiol-disulfide isomerase and thioredoxins.
  
 0.873
EDZ47496.1
Pyridine nucleotide-disulfide oxidoreductase family protein; [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.
    
 0.864
selD
Selenide, water dikinase; [O] COG0309 Hydrogenase maturation factor.
    
 0.864
gcvP_1
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
 0.853
gcvP_2
[E] COG1003 Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain.
     
 0.853
Your Current Organism:
Rhodobacterales bacterium Y4I
NCBI taxonomy Id: 439496
Other names: R. bacterium Y4I
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