Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDZ48066.1Transcriptional regulator, IclR family; [K] COG1414 Transcriptional regulator. (259 aa)    
Predicted Functional Partners:
EDZ47033.1
Bordetella uptake gene product superfamily; [S] COG3181 Uncharacterized protein conserved in bacteria.
 
  
 0.853
EDZ46838.1
Conserved hypothetical protein.
 
     0.799
EDZ46306.1
Membrane protein; [S] COG3333 Uncharacterized protein conserved in bacteria.
 
     0.788
RBY4I_78
[E] COG2049 Allophanate hydrolase subunit 1.
  
    0.770
EDZ46553.1
Aminotransferase class-III; [E] COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
  0.752
EDZ48188.1
Beta-ketoadipate pathway transcriptional regulator, PcaR/PcaU/PobR family; [K] COG1414 Transcriptional regulator.
  
     0.750
EDZ47261.1
N-6 Adenine-specific DNA methylase; [S] COG5441 Uncharacterized conserved protein.
 
     0.733
EDZ48069.1
Transcriptional regulator, GntR family; [K] COG1802 Transcriptional regulators.
  
    0.703
RBY4I_777
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
     
  0.688
EDZ46376.1
Dehydrogenase E1 component family; [C] COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit.
     
  0.670
Your Current Organism:
Rhodobacterales bacterium Y4I
NCBI taxonomy Id: 439496
Other names: R. bacterium Y4I
Server load: low (20%) [HD]