STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDZ48277.1Dihydroorotate dehydrogenase family protein; [C] COG1145 Ferredoxin. (434 aa)    
Predicted Functional Partners:
RBY4I_744
FAD-dependent pyridine nucleotide-disulphide oxidoreductase; [O] COG0492 Thioredoxin reductase.
 0.999
hydA_1
Dihydropyrimidinase; [F] COG0044 Dihydroorotase and related cyclic amidohydrolases.
 
 0.996
hydA_2
Dihydropyrimidinase; [C] COG1229 Formylmethanofuran dehydrogenase subunit A.
 
 0.996
EDZ46845.1
[ER] COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases.
 
 0.995
fdhB
Formate dehydrogenase, beta subunit; [C] COG4656 Predicted NADH:ubiquinone oxidoreductase, subunit RnfC.
   
 0.988
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 0.981
carB
Carbamoyl-phosphate synthase, large subunit; [I] COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit; Belongs to the CarB family.
  
 0.981
RBY4I_257
Dihydroorotase; [F] COG1001 Adenine deaminase.
  
 0.970
fdhA
Formate dehydrogenase, alpha subunit; [C] COG1034 NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G); Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
   
 0.957
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
 
 0.949
Your Current Organism:
Rhodobacterales bacterium Y4I
NCBI taxonomy Id: 439496
Other names: R. bacterium Y4I
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