STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDZ48437.1HAD-superfamily hydrolase subfamily IA, variant 3; [R] COG0637 Predicted phosphatase/phosphohexomutase. (209 aa)    
Predicted Functional Partners:
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
    
 0.853
EDZ47639.1
Haloacetate dehalogenase H-1; [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
   
 
 0.832
EDZ45896.1
Integral membrane protein; [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily.
      0.831
EDZ47645.1
Alpha/beta hydrolase fold; [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
  
 
 0.822
EDZ46615.1
[E] COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog.
       0.772
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
    
  0.689
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.669
fghA
S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde.
   
   0.636
EDZ48642.1
YaiI/YqxD family protein; [S] COG1671 Uncharacterized protein conserved in bacteria; Belongs to the UPF0178 family.
       0.624
EDZ48614.1
Nucleotidyltransferase family protein; [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains).
 
 
  0.538
Your Current Organism:
Rhodobacterales bacterium Y4I
NCBI taxonomy Id: 439496
Other names: R. bacterium Y4I
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