STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDZ48564.1Isocitrate dehydrogenase, NADP-dependent; [C] COG2838 Monomeric isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. (728 aa)    
Predicted Functional Partners:
EDZ47415.1
4Fe-4S ferredoxin, iron-sulfur binding; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
  
 
 0.961
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
  
 0.961
EDZ48643.1
Hypothetical protein; [C] COG2218 Formylmethanofuran dehydrogenase subunit C; Conserved region in glutamate synthase family.
     
 0.906
acnA
Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
 
 
 0.904
EDZ44986.1
Aconitase family (aconitate hydratase); [E] COG0065 3-isopropylmalate dehydratase large subunit.
  
 
 0.897
purB
Adenylosuccinate lyase; [C] COG0114 Fumarase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
   
  0.878
sucA
[C] COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes.
   
 
 0.855
argH
Argininosuccinate lyase; [C] COG0114 Fumarase.
     
 0.830
EDZ47620.1
L-aspartate oxidase; [C] COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.
    
  0.825
RBY4I_269
2-oxoacid:ferredoxin/flavodoxin oxidoreductase, gamma subunit domain protein; [C] COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit.
  
 
 0.812
Your Current Organism:
Rhodobacterales bacterium Y4I
NCBI taxonomy Id: 439496
Other names: R. bacterium Y4I
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