Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
amnAMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. (488 aa)    
Predicted Functional Partners:
ade
Adenine deaminase; [Q] COG1228 Imidazolonepropionase and related amidohydrolases; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
    
 0.955
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
 0.837
mtnP
Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
    
 0.788
EDZ46143.1
[S] COG1496 Uncharacterized conserved protein; Belongs to the multicopper oxidase YfiH/RL5 family.
    
 0.749
purB
Adenylosuccinate lyase; [C] COG0114 Fumarase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
   
 
  0.743
deoD
[F] COG0775 Nucleoside phosphorylase.
     
  0.742
surE
5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
  0.742
RBY4I_460
MazG family protein; [R] COG1694 Predicted pyrophosphatase.
     
  0.742
hup
DNA-binding protein HU; [L] COG0776 Bacterial nucleoid DNA-binding protein; Belongs to the bacterial histone-like protein family.
       0.617
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
    
 0.610
Your Current Organism:
Rhodobacterales bacterium Y4I
NCBI taxonomy Id: 439496
Other names: R. bacterium Y4I
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