STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RBY4I_487Conserved hypothetical protein. (300 aa)    
Predicted Functional Partners:
EDZ48482.1
Endonuclease; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
 
 
 0.993
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.988
RBY4I_519
Molecular chaperone, DnaK; [O] COG0443 Molecular chaperone.
   
 0.988
groL_2
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 0.984
groL_1
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 0.984
RBY4I_125
DnaJ N-terminal domain:DnaJ C terminal domain; [O] COG2214 DnaJ-class molecular chaperone.
  
 0.965
EDZ47345.1
DnaJ domain protein; [O] COG2214 DnaJ-class molecular chaperone.
  
 0.965
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 0.965
cyaF_1
[T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain).
  
 0.948
RBY4I_444
Adenylate cyclase Cya3; [R] COG0457 FOG: TPR repeat.
  
 0.948
Your Current Organism:
Rhodobacterales bacterium Y4I
NCBI taxonomy Id: 439496
Other names: R. bacterium Y4I
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