| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDZ46225.1 | RBY4I_778 | RBY4I_1437 | RBY4I_778 | Conserved hypothetical protein; [K] COG0583 Transcriptional regulator; Belongs to the UPF0102 family. | Cyclic nucleotide-binding protein; [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases. | 0.542 |
| EDZ46225.1 | RBY4I_937 | RBY4I_1437 | RBY4I_937 | Conserved hypothetical protein; [K] COG0583 Transcriptional regulator; Belongs to the UPF0102 family. | Extracellular ligand-binding receptor; [E] COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component. | 0.666 |
| EDZ46225.1 | glnD | RBY4I_1437 | RBY4I_1774 | Conserved hypothetical protein; [K] COG0583 Transcriptional regulator; Belongs to the UPF0102 family. | protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | 0.666 |
| EDZ46225.1 | mviN | RBY4I_1437 | RBY4I_497 | Conserved hypothetical protein; [K] COG0583 Transcriptional regulator; Belongs to the UPF0102 family. | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.661 |
| EDZ46225.1 | rsmI | RBY4I_1437 | RBY4I_3874 | Conserved hypothetical protein; [K] COG0583 Transcriptional regulator; Belongs to the UPF0102 family. | Conserved hypothetical protein TIGR00096; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.831 |
| EDZ47275.1 | EDZ48727.1 | RBY4I_2493 | RBY4I_3950 | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; [M] COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; [M] COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.759 |
| EDZ47275.1 | murA | RBY4I_2493 | RBY4I_506 | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; [M] COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.780 |
| EDZ47275.1 | mviN | RBY4I_2493 | RBY4I_497 | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; [M] COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.892 |
| EDZ48727.1 | EDZ47275.1 | RBY4I_3950 | RBY4I_2493 | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; [M] COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; [M] COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.759 |
| EDZ48727.1 | murA | RBY4I_3950 | RBY4I_506 | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; [M] COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.780 |
| EDZ48727.1 | mviN | RBY4I_3950 | RBY4I_497 | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; [M] COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.892 |
| RBY4I_778 | EDZ46225.1 | RBY4I_778 | RBY4I_1437 | Cyclic nucleotide-binding protein; [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases. | Conserved hypothetical protein; [K] COG0583 Transcriptional regulator; Belongs to the UPF0102 family. | 0.542 |
| RBY4I_778 | RBY4I_937 | RBY4I_778 | RBY4I_937 | Cyclic nucleotide-binding protein; [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases. | Extracellular ligand-binding receptor; [E] COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component. | 0.765 |
| RBY4I_778 | glnD | RBY4I_778 | RBY4I_1774 | Cyclic nucleotide-binding protein; [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases. | protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | 0.762 |
| RBY4I_778 | mviN | RBY4I_778 | RBY4I_497 | Cyclic nucleotide-binding protein; [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases. | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.773 |
| RBY4I_778 | rsmI | RBY4I_778 | RBY4I_3874 | Cyclic nucleotide-binding protein; [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases. | Conserved hypothetical protein TIGR00096; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.542 |
| RBY4I_937 | EDZ46225.1 | RBY4I_937 | RBY4I_1437 | Extracellular ligand-binding receptor; [E] COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component. | Conserved hypothetical protein; [K] COG0583 Transcriptional regulator; Belongs to the UPF0102 family. | 0.666 |
| RBY4I_937 | RBY4I_778 | RBY4I_937 | RBY4I_778 | Extracellular ligand-binding receptor; [E] COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component. | Cyclic nucleotide-binding protein; [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases. | 0.765 |
| RBY4I_937 | glnD | RBY4I_937 | RBY4I_1774 | Extracellular ligand-binding receptor; [E] COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component. | protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | 0.831 |
| RBY4I_937 | mviN | RBY4I_937 | RBY4I_497 | Extracellular ligand-binding receptor; [E] COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component. | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.823 |