Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RBY4I_509Transcriptional regulator, LysR family; [K] COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (301 aa)    
Predicted Functional Partners:
EDZ46880.1
[K] COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.576
metF_2
[E] COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
    0.551
EDZ44997.1
Transcriptional regulator, LysR family; [K] COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.539
folE2
Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate.
  
     0.515
RBY4I_226
Transcriptional regulator, LysR family; [K] COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.496
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.479
EDZ44975.1
Transcriptional regulator, LysR family; [K] COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.443
EDZ46575.1
RNA polymerase, sigma 32 subunit, RpoH; [K] COG1191 DNA-directed RNA polymerase specialized sigma subunit; Belongs to the sigma-70 factor family.
  
 
   0.428
EDZ46944.1
Thioesterase family protein; [Q] COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism.
       0.422
pcaQ
Pca operon transcription factor PcaQ; [K] COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.404
Your Current Organism:
Rhodobacterales bacterium Y4I
NCBI taxonomy Id: 439496
Other names: R. bacterium Y4I
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