STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RBY4I_530[H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase. (248 aa)    
Predicted Functional Partners:
pyc
Pyruvate carboxylase; [I] COG0511 Biotin carboxyl carrier protein.
 
 
 0.957
EDZ47377.1
[I] COG0439 Biotin carboxylase.
  
 0.949
RBY4I_777
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
   
 0.947
accB
acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 
 
 0.933
EDZ48291.1
Acetyl-/propionyl-coenzyme A carboxylase alpha chain; [C] COG1038 Pyruvate carboxylase.
 
  
 0.912
EDZ48372.1
[R] COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily.
      0.910
accC
acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
  
 0.906
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
 
 0.904
EDZ47850.1
Acetyl-/propionyl-coenzyme A carboxylase alpha chain; [EF] COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ).
 
  
 0.903
EDZ46878.1
RimK-like ATP-grasp domain family; [C] COG1038 Pyruvate carboxylase.
 
  
 0.900
Your Current Organism:
Rhodobacterales bacterium Y4I
NCBI taxonomy Id: 439496
Other names: R. bacterium Y4I
Server load: low (28%) [HD]