STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RBY4I_536Conserved domain protein. (72 aa)    
Predicted Functional Partners:
RBY4I_437
Conserved hypothetical protein.
  
     0.612
RBY4I_247
[E] COG4583 Sarcosine oxidase gamma subunit.
  
     0.610
EDZ47055.1
Conserved hypothetical protein.
  
     0.604
EDZ45934.1
Conserved hypothetical protein.
  
     0.507
ruvC
Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
       0.492
ruvA
Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
       0.482
EDZ46704.1
Conserved hypothetical protein.
  
     0.470
EDZ48013.1
Conserved hypothetical protein.
  
     0.444
EDZ46902.1
High-affinity nickel-transporter; [R] COG2215 ABC-type uncharacterized transport system, permease component; Belongs to the NiCoT transporter (TC 2.A.52) family.
  
     0.431
RBY4I_604
Peptidase M23B; [D] COG4942 Membrane-bound metallopeptidase.
  
     0.422
Your Current Organism:
Rhodobacterales bacterium Y4I
NCBI taxonomy Id: 439496
Other names: R. bacterium Y4I
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