STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ilvE_2[EH] COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase. (302 aa)    
Predicted Functional Partners:
EDZ45912.1
Conserved hypothetical protein.
     0.994
ilvD
[EG] COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the IlvD/Edd family.
  
 0.843
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
 
 0.839
EDZ46602.1
2-isopropylmalate synthase/homocitrate synthase family protein; [E] COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 0.816
RBY4I_756
Proline dehydrogenase family; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
   
 0.796
EDZ46354.1
Aminotransferase, class III family; [E] COG4992 Ornithine/acetylornithine aminotransferase.
  
 
 0.789
edd
Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.
  
 0.758
mvaB
hydroxymethylglutaryl-CoA lyase; [C] COG5016 Pyruvate/oxaloacetate carboxyltransferase.
  
 0.723
EDZ46376.1
Dehydrogenase E1 component family; [C] COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit.
  
 0.716
ilvN
[E] COG0440 Acetolactate synthase, small (regulatory) subunit.
  
 0.657
Your Current Organism:
Rhodobacterales bacterium Y4I
NCBI taxonomy Id: 439496
Other names: R. bacterium Y4I
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