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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hemF[H] COG0408 Coproporphyrinogen III oxidase. (297 aa)    
Predicted Functional Partners:
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 0.935
EDZ46550.1
[S] COG1981 Predicted membrane protein; membrane protein rhos4_28450.
 
  
 0.847
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
 
  
 0.773
EDZ47085.1
Short-chain dehydrogenase/reductase SDR; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
       0.741
EDZ46106.1
Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
    
 0.705
hemB
[H] COG0113 Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.640
hemN
[H] COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; Belongs to the anaerobic coproporphyrinogen-III oxidase family.
    
 0.637
RBY4I_727
Coproporphyrinogen III oxidase, anaerobic 2; [H] COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases.
    
 0.637
EDZ46796.1
Methyltransferase small; [J] COG2813 16S RNA G1207 methylase RsmC; Belongs to the methyltransferase superfamily.
       0.618
clpS
ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.
     
 0.617
Your Current Organism:
Rhodobacterales bacterium Y4I
NCBI taxonomy Id: 439496
Other names: R. bacterium Y4I
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