STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mclA_1[G] COG2301 Citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family. (325 aa)    
Predicted Functional Partners:
EDZ46339.1
MaoC family protein; [I] COG2030 Acyl dehydratase.
 
 
 0.837
EDZ47453.1
Phosphate acetyl/butyryl transferase subfamily, putative; [C] COG0281 Malic enzyme.
  
 
 0.795
RBY4I_385
Phosphate acetyl/butyryl transferase subfamily, putative; [C] COG0281 Malic enzyme.
  
 
 0.795
ccrA
crotonyl-CoA reductase; [R] COG1064 Zn-dependent alcohol dehydrogenases.
 
 
 0.658
fucA
L-fuculose phosphate aldolase; [G] COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases.
   
    0.646
EDZ47828.1
Class II aldolase/adducin N-terminal domain protein; [G] COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases.
   
    0.646
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
    
 0.645
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 
 0.625
sucC-2
malate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
    
 0.620
sucD_1
succinyl-CoA synthase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.617
Your Current Organism:
Rhodobacterales bacterium Y4I
NCBI taxonomy Id: 439496
Other names: R. bacterium Y4I
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