| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RBY4I_946 | ddsA | RBY4I_946 | RBY4I_781 | Polyprenyl synthetase; [H] COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | Decaprenyl diphosphate synthase; [H] COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.818 |
| RBY4I_946 | dxr | RBY4I_946 | RBY4I_1925 | Polyprenyl synthetase; [H] COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.549 |
| RBY4I_946 | uppS | RBY4I_946 | RBY4I_746 | Polyprenyl synthetase; [H] COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | Undecaprenyl pyrophosphate synthetase 1; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.916 |
| cdsA | dxr | RBY4I_2510 | RBY4I_1925 | Phosphatidate cytidylyltransferase; [I] COG0575 CDP-diglyceride synthetase; Belongs to the CDS family. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.972 |
| cdsA | frr | RBY4I_2510 | RBY4I_1178 | Phosphatidate cytidylyltransferase; [I] COG0575 CDP-diglyceride synthetase; Belongs to the CDS family. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.874 |
| cdsA | pyrH | RBY4I_2510 | RBY4I_3547 | Phosphatidate cytidylyltransferase; [I] COG0575 CDP-diglyceride synthetase; Belongs to the CDS family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.896 |
| cdsA | rseP | RBY4I_2510 | RBY4I_2517 | Phosphatidate cytidylyltransferase; [I] COG0575 CDP-diglyceride synthetase; Belongs to the CDS family. | RIP metalloprotease RseP; [M] COG0750 Predicted membrane-associated Zn-dependent proteases 1. | 0.924 |
| cdsA | uppS | RBY4I_2510 | RBY4I_746 | Phosphatidate cytidylyltransferase; [I] COG0575 CDP-diglyceride synthetase; Belongs to the CDS family. | Undecaprenyl pyrophosphate synthetase 1; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.989 |
| ddsA | RBY4I_946 | RBY4I_781 | RBY4I_946 | Decaprenyl diphosphate synthase; [H] COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | Polyprenyl synthetase; [H] COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.818 |
| ddsA | uppS | RBY4I_781 | RBY4I_746 | Decaprenyl diphosphate synthase; [H] COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | Undecaprenyl pyrophosphate synthetase 1; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.932 |
| dxr | RBY4I_946 | RBY4I_1925 | RBY4I_946 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Polyprenyl synthetase; [H] COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.549 |
| dxr | cdsA | RBY4I_1925 | RBY4I_2510 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Phosphatidate cytidylyltransferase; [I] COG0575 CDP-diglyceride synthetase; Belongs to the CDS family. | 0.972 |
| dxr | frr | RBY4I_1925 | RBY4I_1178 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.851 |
| dxr | nusA | RBY4I_1925 | RBY4I_2997 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | 0.575 |
| dxr | proS | RBY4I_1925 | RBY4I_3508 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro); Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily. | 0.525 |
| dxr | pyrH | RBY4I_1925 | RBY4I_3547 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.717 |
| dxr | rseP | RBY4I_1925 | RBY4I_2517 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | RIP metalloprotease RseP; [M] COG0750 Predicted membrane-associated Zn-dependent proteases 1. | 0.915 |
| dxr | uppS | RBY4I_1925 | RBY4I_746 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Undecaprenyl pyrophosphate synthetase 1; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.984 |
| frr | cdsA | RBY4I_1178 | RBY4I_2510 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Phosphatidate cytidylyltransferase; [I] COG0575 CDP-diglyceride synthetase; Belongs to the CDS family. | 0.874 |
| frr | dxr | RBY4I_1178 | RBY4I_1925 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.851 |