| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDZ47275.1 | EDZ48643.1 | RBY4I_2493 | RBY4I_3866 | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; [M] COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Hypothetical protein; [C] COG2218 Formylmethanofuran dehydrogenase subunit C; Conserved region in glutamate synthase family. | 0.516 |
| EDZ47275.1 | EDZ48727.1 | RBY4I_2493 | RBY4I_3950 | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; [M] COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; [M] COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.759 |
| EDZ47275.1 | glmM | RBY4I_2493 | RBY4I_391 | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; [M] COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.889 |
| EDZ47275.1 | glmS | RBY4I_2493 | RBY4I_749 | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; [M] COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.828 |
| EDZ47275.1 | glmU | RBY4I_2493 | RBY4I_3263 | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; [M] COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.835 |
| EDZ47275.1 | pgi | RBY4I_2493 | RBY4I_395 | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; [M] COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | [G] COG0166 Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.944 |
| EDZ47275.1 | purF | RBY4I_2493 | RBY4I_2029 | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; [M] COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.598 |
| EDZ48643.1 | EDZ47275.1 | RBY4I_3866 | RBY4I_2493 | Hypothetical protein; [C] COG2218 Formylmethanofuran dehydrogenase subunit C; Conserved region in glutamate synthase family. | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; [M] COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.516 |
| EDZ48643.1 | EDZ48727.1 | RBY4I_3866 | RBY4I_3950 | Hypothetical protein; [C] COG2218 Formylmethanofuran dehydrogenase subunit C; Conserved region in glutamate synthase family. | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; [M] COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.516 |
| EDZ48643.1 | carA | RBY4I_3866 | RBY4I_2916 | Hypothetical protein; [C] COG2218 Formylmethanofuran dehydrogenase subunit C; Conserved region in glutamate synthase family. | Carbamoyl-phosphate synthase, small subunit; [F] COG0518 GMP synthase - Glutamine amidotransferase domain; Belongs to the CarA family. | 0.827 |
| EDZ48643.1 | carB | RBY4I_3866 | RBY4I_3135 | Hypothetical protein; [C] COG2218 Formylmethanofuran dehydrogenase subunit C; Conserved region in glutamate synthase family. | Carbamoyl-phosphate synthase, large subunit; [I] COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit; Belongs to the CarB family. | 0.910 |
| EDZ48643.1 | glmM | RBY4I_3866 | RBY4I_391 | Hypothetical protein; [C] COG2218 Formylmethanofuran dehydrogenase subunit C; Conserved region in glutamate synthase family. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.405 |
| EDZ48643.1 | glmS | RBY4I_3866 | RBY4I_749 | Hypothetical protein; [C] COG2218 Formylmethanofuran dehydrogenase subunit C; Conserved region in glutamate synthase family. | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.900 |
| EDZ48643.1 | purF | RBY4I_3866 | RBY4I_2029 | Hypothetical protein; [C] COG2218 Formylmethanofuran dehydrogenase subunit C; Conserved region in glutamate synthase family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.834 |
| EDZ48727.1 | EDZ47275.1 | RBY4I_3950 | RBY4I_2493 | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; [M] COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; [M] COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.759 |
| EDZ48727.1 | EDZ48643.1 | RBY4I_3950 | RBY4I_3866 | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; [M] COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Hypothetical protein; [C] COG2218 Formylmethanofuran dehydrogenase subunit C; Conserved region in glutamate synthase family. | 0.516 |
| EDZ48727.1 | glmM | RBY4I_3950 | RBY4I_391 | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; [M] COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.889 |
| EDZ48727.1 | glmS | RBY4I_3950 | RBY4I_749 | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; [M] COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.828 |
| EDZ48727.1 | glmU | RBY4I_3950 | RBY4I_3263 | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; [M] COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.835 |
| EDZ48727.1 | pgi | RBY4I_3950 | RBY4I_395 | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; [M] COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | [G] COG0166 Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.944 |