| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDZ48229.1 | RBY4I_778 | RBY4I_3449 | RBY4I_778 | Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | Cyclic nucleotide-binding protein; [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases. | 0.702 |
| EDZ48229.1 | RBY4I_937 | RBY4I_3449 | RBY4I_937 | Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | Extracellular ligand-binding receptor; [E] COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component. | 0.536 |
| EDZ48229.1 | glnD | RBY4I_3449 | RBY4I_1774 | Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | 0.536 |
| EDZ48229.1 | mviN | RBY4I_3449 | RBY4I_497 | Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.543 |
| EDZ48643.1 | EDZ48662.1 | RBY4I_3866 | RBY4I_3885 | Hypothetical protein; [C] COG2218 Formylmethanofuran dehydrogenase subunit C; Conserved region in glutamate synthase family. | KR domain family; [IQ] COG0304 3-oxoacyl-(acyl-carrier-protein) synthase. | 0.866 |
| EDZ48643.1 | RBY4I_756 | RBY4I_3866 | RBY4I_756 | Hypothetical protein; [C] COG2218 Formylmethanofuran dehydrogenase subunit C; Conserved region in glutamate synthase family. | Proline dehydrogenase family; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.871 |
| EDZ48643.1 | RBY4I_778 | RBY4I_3866 | RBY4I_778 | Hypothetical protein; [C] COG2218 Formylmethanofuran dehydrogenase subunit C; Conserved region in glutamate synthase family. | Cyclic nucleotide-binding protein; [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases. | 0.857 |
| EDZ48643.1 | glnD | RBY4I_3866 | RBY4I_1774 | Hypothetical protein; [C] COG2218 Formylmethanofuran dehydrogenase subunit C; Conserved region in glutamate synthase family. | protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | 0.578 |
| EDZ48643.1 | rpoB | RBY4I_3866 | RBY4I_1412 | Hypothetical protein; [C] COG2218 Formylmethanofuran dehydrogenase subunit C; Conserved region in glutamate synthase family. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.427 |
| EDZ48662.1 | EDZ48643.1 | RBY4I_3885 | RBY4I_3866 | KR domain family; [IQ] COG0304 3-oxoacyl-(acyl-carrier-protein) synthase. | Hypothetical protein; [C] COG2218 Formylmethanofuran dehydrogenase subunit C; Conserved region in glutamate synthase family. | 0.866 |
| EDZ48662.1 | RBY4I_444 | RBY4I_3885 | RBY4I_444 | KR domain family; [IQ] COG0304 3-oxoacyl-(acyl-carrier-protein) synthase. | Adenylate cyclase Cya3; [R] COG0457 FOG: TPR repeat. | 0.736 |
| EDZ48662.1 | RBY4I_756 | RBY4I_3885 | RBY4I_756 | KR domain family; [IQ] COG0304 3-oxoacyl-(acyl-carrier-protein) synthase. | Proline dehydrogenase family; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.635 |
| EDZ48662.1 | RBY4I_778 | RBY4I_3885 | RBY4I_778 | KR domain family; [IQ] COG0304 3-oxoacyl-(acyl-carrier-protein) synthase. | Cyclic nucleotide-binding protein; [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases. | 0.819 |
| EDZ48662.1 | cyaF_1 | RBY4I_3885 | RBY4I_1989 | KR domain family; [IQ] COG0304 3-oxoacyl-(acyl-carrier-protein) synthase. | [T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain). | 0.736 |
| EDZ48662.1 | rpoB | RBY4I_3885 | RBY4I_1412 | KR domain family; [IQ] COG0304 3-oxoacyl-(acyl-carrier-protein) synthase. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.570 |
| RBY4I_444 | EDZ48662.1 | RBY4I_444 | RBY4I_3885 | Adenylate cyclase Cya3; [R] COG0457 FOG: TPR repeat. | KR domain family; [IQ] COG0304 3-oxoacyl-(acyl-carrier-protein) synthase. | 0.736 |
| RBY4I_444 | RBY4I_778 | RBY4I_444 | RBY4I_778 | Adenylate cyclase Cya3; [R] COG0457 FOG: TPR repeat. | Cyclic nucleotide-binding protein; [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases. | 0.797 |
| RBY4I_444 | cyaF_1 | RBY4I_444 | RBY4I_1989 | Adenylate cyclase Cya3; [R] COG0457 FOG: TPR repeat. | [T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain). | 0.915 |
| RBY4I_444 | rpoB | RBY4I_444 | RBY4I_1412 | Adenylate cyclase Cya3; [R] COG0457 FOG: TPR repeat. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.699 |
| RBY4I_756 | EDZ48643.1 | RBY4I_756 | RBY4I_3866 | Proline dehydrogenase family; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Hypothetical protein; [C] COG2218 Formylmethanofuran dehydrogenase subunit C; Conserved region in glutamate synthase family. | 0.871 |