STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cobHprecorrin-8X methylmutase; [H] COG2082 Precorrin isomerase. (209 aa)    
Predicted Functional Partners:
cobJ
precorrin-3B C17-methyltransferase; [H] COG0007 Uroporphyrinogen-III methylase.
  
 0.999
cobl
precorrin-6Y C(5,15)-methyltransferase (decarboxylating); [H] COG2242 Precorrin-6B methylase 2.
 
 
 0.998
cobI
[H] COG2243 Precorrin-2 methylase; Belongs to the precorrin methyltransferase family.
 
 
 0.997
cobG
precorrin-3B synthase; [P] COG0155 Sulfite reductase, beta subunit (hemoprotein).
 
 0.996
cobB
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
 0.993
cobM
Precorrin-4 C11-methyltransferase; [H] COG2243 Precorrin-2 methylase; Belongs to the precorrin methyltransferase family.
 
 
 0.991
cobK
[H] COG2099 Precorrin-6x reductase.
 
 
 0.990
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
 0.990
cobF
precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A.
 
 
 0.986
cobN
Cobaltochelatase, CobN subunit; [H] COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases.
 
  
 0.976
Your Current Organism:
Rhodobacterales bacterium Y4I
NCBI taxonomy Id: 439496
Other names: R. bacterium Y4I
Server load: medium (44%) [HD]