| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDZ46664.1 | EDZ48662.1 | RBY4I_1881 | RBY4I_3885 | BolA family protein; [K] COG5007 Predicted transcriptional regulator, BolA superfamily; Belongs to the BolA/IbaG family. | KR domain family; [IQ] COG0304 3-oxoacyl-(acyl-carrier-protein) synthase. | 0.718 |
| EDZ46664.1 | RBY4I_654 | RBY4I_1881 | RBY4I_654 | BolA family protein; [K] COG5007 Predicted transcriptional regulator, BolA superfamily; Belongs to the BolA/IbaG family. | Hypothetical protein. | 0.791 |
| EDZ46664.1 | RBY4I_875 | RBY4I_1881 | RBY4I_875 | BolA family protein; [K] COG5007 Predicted transcriptional regulator, BolA superfamily; Belongs to the BolA/IbaG family. | Hypothetical protein; [S] COG1357 Uncharacterized low-complexity proteins; pentapeptide repeat. | 0.584 |
| EDZ46664.1 | purL | RBY4I_1881 | RBY4I_3620 | BolA family protein; [K] COG5007 Predicted transcriptional regulator, BolA superfamily; Belongs to the BolA/IbaG family. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.526 |
| EDZ47732.1 | EDZ48662.1 | RBY4I_2951 | RBY4I_3885 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | KR domain family; [IQ] COG0304 3-oxoacyl-(acyl-carrier-protein) synthase. | 0.817 |
| EDZ47732.1 | RBY4I_460 | RBY4I_2951 | RBY4I_460 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | MazG family protein; [R] COG1694 Predicted pyrophosphatase. | 0.819 |
| EDZ47732.1 | RBY4I_875 | RBY4I_2951 | RBY4I_875 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Hypothetical protein; [S] COG1357 Uncharacterized low-complexity proteins; pentapeptide repeat. | 0.531 |
| EDZ47732.1 | folE2 | RBY4I_2951 | RBY4I_1171 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.742 |
| EDZ47732.1 | moaA_1 | RBY4I_2951 | RBY4I_3125 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.749 |
| EDZ47732.1 | ndk | RBY4I_2951 | RBY4I_2865 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.890 |
| EDZ47732.1 | ribB | RBY4I_2951 | RBY4I_533 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.827 |
| EDZ48662.1 | EDZ46664.1 | RBY4I_3885 | RBY4I_1881 | KR domain family; [IQ] COG0304 3-oxoacyl-(acyl-carrier-protein) synthase. | BolA family protein; [K] COG5007 Predicted transcriptional regulator, BolA superfamily; Belongs to the BolA/IbaG family. | 0.718 |
| EDZ48662.1 | EDZ47732.1 | RBY4I_3885 | RBY4I_2951 | KR domain family; [IQ] COG0304 3-oxoacyl-(acyl-carrier-protein) synthase. | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.817 |
| EDZ48662.1 | RBY4I_875 | RBY4I_3885 | RBY4I_875 | KR domain family; [IQ] COG0304 3-oxoacyl-(acyl-carrier-protein) synthase. | Hypothetical protein; [S] COG1357 Uncharacterized low-complexity proteins; pentapeptide repeat. | 0.525 |
| EDZ48662.1 | ndk | RBY4I_3885 | RBY4I_2865 | KR domain family; [IQ] COG0304 3-oxoacyl-(acyl-carrier-protein) synthase. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.667 |
| EDZ48662.1 | purL | RBY4I_3885 | RBY4I_3620 | KR domain family; [IQ] COG0304 3-oxoacyl-(acyl-carrier-protein) synthase. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.424 |
| EDZ48662.1 | ribB | RBY4I_3885 | RBY4I_533 | KR domain family; [IQ] COG0304 3-oxoacyl-(acyl-carrier-protein) synthase. | Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.410 |
| RBY4I_460 | EDZ47732.1 | RBY4I_460 | RBY4I_2951 | MazG family protein; [R] COG1694 Predicted pyrophosphatase. | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.819 |
| RBY4I_460 | RBY4I_875 | RBY4I_460 | RBY4I_875 | MazG family protein; [R] COG1694 Predicted pyrophosphatase. | Hypothetical protein; [S] COG1357 Uncharacterized low-complexity proteins; pentapeptide repeat. | 0.530 |
| RBY4I_460 | folE2 | RBY4I_460 | RBY4I_1171 | MazG family protein; [R] COG1694 Predicted pyrophosphatase. | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.742 |