clpC2 protein (Crocosphaera subtropica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

clpC2

ATP-dependent Clp protease, regulatory subunit; Belongs to the ClpA/ClpB family. (789 aa)

Predicted Functional Partners:

grpE

0.803

dnaK3

0.774

cce_2464

0.774

dnaK2

0.771

dnaK1

0.759

htpG

0.733

cce_1424

0.732

hspA2

0.705

hspA1

0.705

clpP1

0.644

Your Current Organism:

Crocosphaera subtropica

NCBI taxonomy Id: 43989
Other names: C. subtropica ATCC 51142, Crocosphaera subtropica ATCC 51142, Cyanothece sp. ATCC 51142, Cyanothece sp. BH68, Cyanothece sp. BH68K

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
cce_1424	clpC2	cce_1424	cce_1001	Hypothetical protein.	ATP-dependent Clp protease, regulatory subunit; Belongs to the ClpA/ClpB family.	0.732
cce_1424	grpE	cce_1424	cce_4005	Hypothetical protein.	Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depen [...]	0.918
cce_1424	hspA1	cce_1424	cce_4697	Hypothetical protein.	Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family.	0.450
cce_1424	hspA2	cce_1424	cce_4669	Hypothetical protein.	Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family.	0.450
cce_1424	htpG	cce_1424	cce_2925	Hypothetical protein.	Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.	0.914
cce_2464	clpC2	cce_2464	cce_1001	Hsp70-like protein; Belongs to the heat shock protein 70 family.	ATP-dependent Clp protease, regulatory subunit; Belongs to the ClpA/ClpB family.	0.774
cce_2464	grpE	cce_2464	cce_4005	Hsp70-like protein; Belongs to the heat shock protein 70 family.	Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depen [...]	0.957
cce_2464	hspA1	cce_2464	cce_4697	Hsp70-like protein; Belongs to the heat shock protein 70 family.	Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family.	0.450
cce_2464	hspA2	cce_2464	cce_4669	Hsp70-like protein; Belongs to the heat shock protein 70 family.	Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family.	0.450
cce_2464	htpG	cce_2464	cce_2925	Hsp70-like protein; Belongs to the heat shock protein 70 family.	Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.	0.948
clpC2	cce_1424	cce_1001	cce_1424	ATP-dependent Clp protease, regulatory subunit; Belongs to the ClpA/ClpB family.	Hypothetical protein.	0.732
clpC2	cce_2464	cce_1001	cce_2464	ATP-dependent Clp protease, regulatory subunit; Belongs to the ClpA/ClpB family.	Hsp70-like protein; Belongs to the heat shock protein 70 family.	0.774
clpC2	clpP1	cce_1001	cce_0641	ATP-dependent Clp protease, regulatory subunit; Belongs to the ClpA/ClpB family.	ATP-dependent Clp protease, proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	0.644
clpC2	dnaK1	cce_1001	cce_2003	ATP-dependent Clp protease, regulatory subunit; Belongs to the ClpA/ClpB family.	Heat shock protein Hsp70; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.759
clpC2	dnaK2	cce_1001	cce_4004	ATP-dependent Clp protease, regulatory subunit; Belongs to the ClpA/ClpB family.	Heat shock protein Hsp70; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.771
clpC2	dnaK3	cce_1001	cce_1356	ATP-dependent Clp protease, regulatory subunit; Belongs to the ClpA/ClpB family.	Heat shock protein Hsp70; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.774
clpC2	grpE	cce_1001	cce_4005	ATP-dependent Clp protease, regulatory subunit; Belongs to the ClpA/ClpB family.	Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depen [...]	0.803
clpC2	hspA1	cce_1001	cce_4697	ATP-dependent Clp protease, regulatory subunit; Belongs to the ClpA/ClpB family.	Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family.	0.705
clpC2	hspA2	cce_1001	cce_4669	ATP-dependent Clp protease, regulatory subunit; Belongs to the ClpA/ClpB family.	Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family.	0.705
clpC2	htpG	cce_1001	cce_2925	ATP-dependent Clp protease, regulatory subunit; Belongs to the ClpA/ClpB family.	Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.	0.733

page 1 of 4

Server load: low (12%) [HD]

Permalink

Network

Neighborhood

Experiments

Co-occurrence

Databases

Co-expression

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About