Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
hupS[NiFe] uptake hydrogenase small subunit. (320 aa)    
Predicted Functional Partners:
hupL
[NiFe] uptake hydrogenase large subunit.
 0.999
cce_1743
Probable peptidase M52, hydrogen uptake protein.
 
  
 0.878
hypB
Hydrogenase accessory protein.
 
  
 0.833
cce_1854
Unknown.
 
     0.793
hypD
Hydrogenase isoenzymes formation protein.
 
  
 0.780
cce_2897
Unknown; Contains a soluble quinoprotein glucose dehydrogenase domain.
  
     0.773
cce_1857
NifU-like protein.
 
   
 0.762
hypE
Hydrogenase expression/formation protein.
 
   
 0.747
hypF
Hydrogenase maturation protein.
 
 
 
 0.730
rub2
Putative rubredoxin.
  
 
 0.663
Your Current Organism:
Crocosphaera subtropica
NCBI taxonomy Id: 43989
Other names: C. subtropica ATCC 51142, Crocosphaera subtropica ATCC 51142, Cyanothece sp. ATCC 51142, Cyanothece sp. BH68, Cyanothece sp. BH68K
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