| node1 | node2 | node1 annotation | node2 annotation | score |
| cce_0539 | cce_0656 | Hypothetical protein; Contains EAL and PAS fold-3 domains. | Two-component hybrid sensor and regulator. | 0.688 |
| cce_0539 | cce_1185 | Hypothetical protein; Contains EAL and PAS fold-3 domains. | Two-component hybrid sensor and regulator. | 0.759 |
| cce_0539 | cce_1186 | Hypothetical protein; Contains EAL and PAS fold-3 domains. | Two-component hybrid sensor and regulator. | 0.754 |
| cce_0539 | cce_1206 | Hypothetical protein; Contains EAL and PAS fold-3 domains. | Hypothetical protein; Contains PAS, GGDEF, and GAF domains. | 0.892 |
| cce_0539 | cce_1521 | Hypothetical protein; Contains EAL and PAS fold-3 domains. | Unknown; Contains PAS, GGDEF, EAL, Response regulator receiver, CheY-like, and PAS fold-3 domains. | 0.839 |
| cce_0539 | cce_1555 | Hypothetical protein; Contains EAL and PAS fold-3 domains. | Unknown; Contains a GAF domain. | 0.779 |
| cce_0539 | cce_1777 | Hypothetical protein; Contains EAL and PAS fold-3 domains. | Probable two-component hybrid sensor and regulator. | 0.755 |
| cce_0539 | cce_4177 | Hypothetical protein; Contains EAL and PAS fold-3 domains. | Hypothetical protein; Contains a GGDEF domain, Forkhead-associated domain, EAL domain, SMAD/FHA domain, and a PAS fold domain. | 0.938 |
| cce_0539 | cce_4651 | Hypothetical protein; Contains EAL and PAS fold-3 domains. | Hypothetical protein; Contains an EAL signaling domain. | 0.925 |
| cce_0539 | cce_4709 | Hypothetical protein; Contains EAL and PAS fold-3 domains. | Unknown; Contains a GGDEF domain, EAL domain, and PAS fold-3 domain. | 0.745 |
| cce_0656 | cce_0539 | Two-component hybrid sensor and regulator. | Hypothetical protein; Contains EAL and PAS fold-3 domains. | 0.688 |
| cce_0656 | cce_1185 | Two-component hybrid sensor and regulator. | Two-component hybrid sensor and regulator. | 0.997 |
| cce_0656 | cce_1186 | Two-component hybrid sensor and regulator. | Two-component hybrid sensor and regulator. | 0.988 |
| cce_0656 | cce_1206 | Two-component hybrid sensor and regulator. | Hypothetical protein; Contains PAS, GGDEF, and GAF domains. | 0.882 |
| cce_0656 | cce_1521 | Two-component hybrid sensor and regulator. | Unknown; Contains PAS, GGDEF, EAL, Response regulator receiver, CheY-like, and PAS fold-3 domains. | 0.985 |
| cce_0656 | cce_1555 | Two-component hybrid sensor and regulator. | Unknown; Contains a GAF domain. | 0.925 |
| cce_0656 | cce_1777 | Two-component hybrid sensor and regulator. | Probable two-component hybrid sensor and regulator. | 0.997 |
| cce_0656 | cce_4177 | Two-component hybrid sensor and regulator. | Hypothetical protein; Contains a GGDEF domain, Forkhead-associated domain, EAL domain, SMAD/FHA domain, and a PAS fold domain. | 0.974 |
| cce_0656 | cce_4651 | Two-component hybrid sensor and regulator. | Hypothetical protein; Contains an EAL signaling domain. | 0.985 |
| cce_0656 | cce_4709 | Two-component hybrid sensor and regulator. | Unknown; Contains a GGDEF domain, EAL domain, and PAS fold-3 domain. | 0.974 |