Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cce_1472Hypothetical protein; Contains a DnaJ N-terminal four helical 'J' domain. (232 aa)    
Predicted Functional Partners:
dnaK1
Heat shock protein Hsp70; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.908
cce_2464
Hsp70-like protein; Belongs to the heat shock protein 70 family.
 
 0.900
dnaK3
Heat shock protein Hsp70; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.899
dnaK2
Heat shock protein Hsp70; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.895
htpG
Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.
  
 0.880
hoxF
NADH dehydrogenase I chain F.
    
  0.861
cce_0149
Probable protein phosphatase.
  
 
 0.833
cce_3078
Polyketide synthase.
  
 
 0.798
cce_3079
Probable polyketide synthase.
   
 
 0.783
grpE
Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depen [...]
 
 
 0.777
Your Current Organism:
Crocosphaera subtropica
NCBI taxonomy Id: 43989
Other names: C. subtropica ATCC 51142, Crocosphaera subtropica ATCC 51142, Cyanothece sp. ATCC 51142, Cyanothece sp. BH68, Cyanothece sp. BH68K
Server load: low (20%) [HD]