Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
hemB3Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (329 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
 
 0.994
hemL
Glutamate-1-semialdehyde aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
 
 
 0.986
hemD
Bifunctional uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase; Belongs to the precorrin methyltransferase family.
 
 0.975
hemB2
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
  
  
 
0.903
hemB1
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
  
  
 
0.900
hemA
Transfer RNA-Gln reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.856
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 
 0.731
cce_3045
Aminotransferase class-III, putative glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
 0.719
cobA
uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
 
  
 0.661
cce_1488
Hypothetical protein; Contains a cobalamin (vitamin B12) biosynthesis domain, cobW domain.
     
 0.552
Your Current Organism:
Crocosphaera subtropica
NCBI taxonomy Id: 43989
Other names: C. subtropica ATCC 51142, Crocosphaera subtropica ATCC 51142, Cyanothece sp. ATCC 51142, Cyanothece sp. BH68, Cyanothece sp. BH68K
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