Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cce_1820Putative small mechanosensitive ion channel, MscS family. (376 aa)    
Predicted Functional Partners:
cce_1819
Unknown; Contains a MscS Mechanosensitive ion channel domain.
 
    
0.828
cce_1821
Putative HAD-superfamily hydrolase, subfamily IA.
       0.689
cce_3877
Hypothetical protein; Contains a mechanosensitive ion channel, MscS domain.
  
     0.679
cce_4212
rfrA family pentapeptide repeat.
  
     0.590
cce_1483
Hypothetical protein; Contains a MscS Mechanosensitive ion channel domain.
  
     0.518
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
    0.471
cce_1090
Putative Na+/K+/2Cl- cotransporter.
  
     0.451
cce_4799
rfrA family pentapeptide repeat.
  
     0.444
gcvP
Glycine cleavage system protein P; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
    0.418
cce_1979
rfrA family pentapeptide repeat.
  
     0.416
Your Current Organism:
Crocosphaera subtropica
NCBI taxonomy Id: 43989
Other names: C. subtropica ATCC 51142, Crocosphaera subtropica ATCC 51142, Cyanothece sp. ATCC 51142, Cyanothece sp. BH68, Cyanothece sp. BH68K
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.