nnrE protein (Crocosphaera subtropica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

nnrE

Unknown; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P [...] (528 aa)

Predicted Functional Partners:

cce_5005

0.953

deaD

0.889

cce_2592

0.827

cce_0062

0.810

hoxF

0.803

groEL1

0.782

groEL2

0.782

cce_0096

0.781

cce_2950

0.766

cce_3413

0.766

Your Current Organism:

Crocosphaera subtropica

NCBI taxonomy Id: 43989
Other names: C. subtropica ATCC 51142, Crocosphaera subtropica ATCC 51142, Cyanothece sp. ATCC 51142, Cyanothece sp. BH68, Cyanothece sp. BH68K

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
cce_0062	cce_2592	cce_0062	cce_2592	NUDIX hydrolase.	NUDIX hydrolase.	0.923
cce_0062	cce_5005	cce_0062	cce_5005	NUDIX hydrolase.	Hypothetical protein; Contains Helicase, C-terminal, Type III restriction enzyme, res subunit and DEAD/DEAH box helicase, N-terminal domains.	0.665
cce_0062	deaD	cce_0062	cce_4436	NUDIX hydrolase.	ATP-dependent RNA helicase; Belongs to the DEAD box helicase family.	0.510
cce_0062	nnrE	cce_0062	cce_1949	NUDIX hydrolase.	Unknown; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P [...]	0.810
cce_0096	cce_5005	cce_0096	cce_5005	Putative NUDIX hydrolase.	Hypothetical protein; Contains Helicase, C-terminal, Type III restriction enzyme, res subunit and DEAD/DEAH box helicase, N-terminal domains.	0.665
cce_0096	deaD	cce_0096	cce_4436	Putative NUDIX hydrolase.	ATP-dependent RNA helicase; Belongs to the DEAD box helicase family.	0.510
cce_0096	nnrE	cce_0096	cce_1949	Putative NUDIX hydrolase.	Unknown; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P [...]	0.781
cce_2592	cce_0062	cce_2592	cce_0062	NUDIX hydrolase.	NUDIX hydrolase.	0.923
cce_2592	cce_5005	cce_2592	cce_5005	NUDIX hydrolase.	Hypothetical protein; Contains Helicase, C-terminal, Type III restriction enzyme, res subunit and DEAD/DEAH box helicase, N-terminal domains.	0.665
cce_2592	deaD	cce_2592	cce_4436	NUDIX hydrolase.	ATP-dependent RNA helicase; Belongs to the DEAD box helicase family.	0.510
cce_2592	nnrE	cce_2592	cce_1949	NUDIX hydrolase.	Unknown; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P [...]	0.827
cce_2950	cce_5005	cce_2950	cce_5005	Conserved hypothetical protein.	Hypothetical protein; Contains Helicase, C-terminal, Type III restriction enzyme, res subunit and DEAD/DEAH box helicase, N-terminal domains.	0.658
cce_2950	deaD	cce_2950	cce_4436	Conserved hypothetical protein.	ATP-dependent RNA helicase; Belongs to the DEAD box helicase family.	0.494
cce_2950	nnrE	cce_2950	cce_1949	Conserved hypothetical protein.	Unknown; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P [...]	0.766
cce_3413	cce_5005	cce_3413	cce_5005	Hypothetical protein.	Hypothetical protein; Contains Helicase, C-terminal, Type III restriction enzyme, res subunit and DEAD/DEAH box helicase, N-terminal domains.	0.658
cce_3413	deaD	cce_3413	cce_4436	Hypothetical protein.	ATP-dependent RNA helicase; Belongs to the DEAD box helicase family.	0.494
cce_3413	nnrE	cce_3413	cce_1949	Hypothetical protein.	Unknown; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P [...]	0.766
cce_5005	cce_0062	cce_5005	cce_0062	Hypothetical protein; Contains Helicase, C-terminal, Type III restriction enzyme, res subunit and DEAD/DEAH box helicase, N-terminal domains.	NUDIX hydrolase.	0.665
cce_5005	cce_0096	cce_5005	cce_0096	Hypothetical protein; Contains Helicase, C-terminal, Type III restriction enzyme, res subunit and DEAD/DEAH box helicase, N-terminal domains.	Putative NUDIX hydrolase.	0.665
cce_5005	cce_2592	cce_5005	cce_2592	Hypothetical protein; Contains Helicase, C-terminal, Type III restriction enzyme, res subunit and DEAD/DEAH box helicase, N-terminal domains.	NUDIX hydrolase.	0.665

page 1 of 3

Server load: low (8%) [HD]

Permalink

Network

Neighborhood

Experiments

Co-occurrence

Databases

Co-expression

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About