STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemDBifunctional uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase; Belongs to the precorrin methyltransferase family. (503 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
 0.999
hemB2
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 0.969
hemB3
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 0.968
hemB1
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 0.968
cbiL
Precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family.
 
 
 0.952
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
 
 0.949
cobA
uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
 
 
0.937
nirA
Ferredoxin-nitrite reductase; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.935
hemA
Transfer RNA-Gln reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.895
ccsA
Cytochrome c assembly protein; Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
  
    0.874
Your Current Organism:
Crocosphaera subtropica
NCBI taxonomy Id: 43989
Other names: C. subtropica ATCC 51142, Crocosphaera subtropica ATCC 51142, Cyanothece sp. ATCC 51142, Cyanothece sp. BH68, Cyanothece sp. BH68K
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